Advacort:

An Effective Dermatological Solution

Composition:

• Advacort 01% Cream: Contains 1mg (01% w/w) Methylprednisolone Aceponate MS per gram
• Advacort 01% Ointment: Contains 1mg (01% w/w) Methylprednisolone Aceponate MS per gram

Description:

• Active Ingredient: Methylprednisolone Aceponate, a synthetic glucocorticoid
• Properties: Anti-inflammatory, immunomodulating
• Mechanism of Action: Alters gene expressions, inhibits cytokines, reduces lymphocytes, induces apoptosis, and influences cell differentiation
• Pharmacokinetics: Gradual concentration decrease in skin layers
• Formulations: Available in Cream and Ointment

Pharmacological Properties:

• Pharmacodynamics: Anti-inflammatory, antipruritic, vasoconstrictive
• Mechanism of Action: Binds to glucocorticoid receptors, inhibits proinflammatory mediators
• Immunosuppressive Action: Inhibits chemotaxis, antimitotic activity
• Vasoconstrictive Activity: Inhibits prostaglandin synthesis

Indications:

• Treats Atopic dermatitis, contact eczema, degenerative eczema, dyshidrotic eczema, vulgar eczema, and psoriasis in adults and children

Adverse Reactions:

• Common: Itching, burning, erythema, vesiculation
• Rare: Atrophy, telangiectasia, striae, acneiform conditions
• Other: Folliculitis, hypertrichosis, perioral dermatitis, hypersensitivity

Drug Interaction: No specific information on interactions with other medications

Overdosage: Excessive dosing may occur with prolonged or intensive topical use

Instructions:

• Store below 30 °C, protect from light and heat
• Keep out of reach of children
• Use as directed by the physician
• For external use only, not for ophthalmic use

Presentations:

• Advacort 01% Cream: 10g aluminum collapsible tube
• Advacort 01% Ointment: 5g aluminum collapsible tube

Advacort offers effective relief for various dermatological conditions while prioritizing patient safety and optimal outcomes.