Conaz Cream: Effective Treatment for Fungal Skin Infections

Conaz Cream, containing Ketoconazole 2%, is a potent antifungal solution designed to combat a variety of fungal skin infections. This comprehensive guide outlines its composition, pharmacological properties, indications, dosage, precautions, and more to ensure effective and safe use.

Composition

• Active Ingredient: Each gram of Conaz Cream contains Ketoconazole BP (2%).

Pharmacological Properties

Mode of Action

• Ketoconazole inhibits ergosterol synthesis, a key component of fungal cell membranes.
• Additionally, its effectiveness in seborrheic dermatitis is linked to reducing Malassezia ovale populations.

Pharmacodynamics

• Exhibits strong antifungal activity against dermatophytes and yeasts.
• Furthermore, it provides rapid relief from itching (pruritus) associated with fungal infections.

Indications

Conaz 2% Cream is recommended for the treatment of:

1. Dermatophyte Infections:
   • Tinea corporis (body ringworm)
   • Tinea cruris (jock itch)
   • Caused by Trichophyton, Microsporon, and Epidermophyton species.
2. Cutaneous Candidiasis: Yeast infections of the skin.
3. Tinea Versicolor: Fungal discoloration of the skin.
4. Seborrheic Dermatitis: Inflammation caused by Malassezia spp.

Note: Suitable for adult use only.

Dosage & Administration

• Mild Infections: Apply a thin layer once daily for one week.
• Severe Infections: May require longer treatment durations.
• Tinea Versicolor: Treat for up to two weeks.
• Seborrheic Dermatitis: Apply twice daily for up to four weeks or until the condition clears.

Adverse Effects

Common side effects may include:

• Itching (pruritus)
• Skin burning
• Erythema (redness) at the application site

If no improvement is observed after four weeks, the diagnosis should be reassessed. In addition, maintaining proper hygiene is essential to control infection sources.

Contraindications

• Hypersensitivity to Ketoconazole or any ingredient in Conaz Cream.

Warnings and Precautions

• Discontinue use if sensitivity or chemical irritation occurs.
• Avoid contact with the eyes or other mucous membranes.
• After prolonged corticosteroid use: Gradually taper steroids over 2-3 weeks to prevent rebound effects.

Drug Interactions

• Currently, no interaction studies have been conducted for Conaz Cream.

Missed Dose

• Apply the missed dose as soon as remembered. However, if it is near the time of the next scheduled dose, skip the missed one and continue the regular routine.

Over-dosage

Excessive application may cause:

• Redness (erythema)
• Swelling (edema)
• Burning sensation

To resolve: Discontinue use immediately.

Storage Instructions

• Store below 30 °C, away from direct light and heat.
• Keep out of reach of children.

Presentation

• Conaz 2% Cream is available in a 10g aluminum collapsible tube.

Conclusion

Conaz Cream, with Ketoconazole 2%, is a trusted treatment for fungal infections, providing relief from itching, redness, and discomfort. For best results, follow the recommended dosage and precautions, and consult a healthcare professional for guidance. With proper use, Conaz Cream can help restore healthy, infection-free skin effectively.