Fusiderm Cream (Fusidic Acid 2% w/w):

Your Solution for Skin Infections

 Description:

Fusiderm Cream, manufactured by Martin Dow, is a potent antibiotic cream containing Fusidic Acid 2% w/w. Fusidic acid exhibits remarkable antibacterial activity, particularly against various gram-positive organisms. Notably, Staphylococci, even those resistant to penicillin and other antibiotics, are highly susceptible to fusidic acid. Fusidic acid, chemically known as (17Z)16β(Acetyloxy)3β,19dihydroxy4β,8,14trimethyl18nor5β,10αcholesta17(20),24dien21oic acid hemihydrate, is an antimicrobial compound produced through the cultivation of specific strains of Fusiderm coccineous

 Composition:

Each gram of Fusiderm Cream contains:

 Fusidic Acid (BP): 2% w/w

 Therapeutic Indications:

Fusiderm Cream is indicated for the treatment of both primary and secondary skin infections caused by Staphylococcus aureus, Streptococcus spp, and Corynebacterium minutissimum. Primary skin infections encompass conditions like impetigo contagions and erythrismal, while secondary skin infections include infected wounds and burns

 Clinical Pharmacology:

Fusidic acid, in addition to targeting Staphylococci, also demonstrates activity against other bacterial species such as various Corynebacterial spp, Neisseria spp, Clostridia spp, and Bacteroides spp

 Mechanism of Action:

Fusidic acid acts by inhibiting protein synthesis, interfering with the transfer of amino acids from aminoacyl RNA to protein on the ribosomes

 Pharmacokinetics:

Fusidic acid can permeate intact human skin, with the extent of penetration influenced by factors such as exposure duration and skin condition. It is primarily excreted in bile, with minimal excretion in urine

 Dosage and Administration:

For uncovered lesions, apply a small amount of Fusidic acid cream 3 or 4 times daily. In the case of covered lesions, less frequent applications (1 or 2 times daily) may be appropriate

 Contraindications:

Fusiderm Cream should not be used in cases of hypersensitivity to the active substance or any of its components

 Warnings & Precautions:

•  Prolonged or recurrent use may elevate the risk of antibiotic resistance and contact sensitization
•  When applying the cream to the face, take care to avoid contact with the eyes, as some components may cause conjunctival irritation
•  Use during pregnancy should be cautious and determined by assessing the benefit to the mother against potential risks to the developing baby

 Overdosage:

Overdosing with Fusidic acid cream is unlikely

 Adverse Effects:

Hypersensitivity reactions and angioedema may occur

 Stability:

Please refer to the expiry date on the packaging for product stability

 Packs:

Fusiderm Cream is available in the following presentation:

 Cream 2% w/w: 15g

 Instructions:

•  Store Fusiderm Cream below 30 °C, protected from light and heat
•  Keep all medicines out of children’s reach
•  This product is to be sold only on the prescription of a registered medical practitioner

 Fusiderm Cream, with its potent antibacterial action, offers a reliable solution for various skin infections. However, it should only be used as directed by a healthcare professional to ensure safe and effective treatment