Predheal Cream: Active Relief for Skin Inflammation

Composition:

Predheal Cream Each gram contains the potent anti-inflammatory corticosteroid Methylprednisolone Aceponate 0.1% w/w.

Description:

• Predheal is a topical medicine (corticosteroid) specifically designed to combat various skin inflammatory issues.  It effectively  tames redness (erythema), skin thickening, bumps, fluid buildup (edema), itching, and burning sensations.
• Ideal for conditions like atopic dermatitis, eczema in children, contact eczema, and various eczema forms,  Predheal provides targeted relief.

Clinical Pharmacology:

• Upon topical application, Predheal exhibits anti-inflammatory, anti-itching, and blood vessel-constricting actions.  It binds to internal glucocorticoid receptors,  triggering lipomodulin production.  This protein blocks inflammatory mediators,bringing relief from skin inflammation and itching.

Percutaneous and Systemic Absorption:

• Slightly more Methylprednisolone Aceponate (approximately 2.5%) gets absorbed through open skin compared to normal skin (0.2-1.5%).
• Occlusive dressings can increase absorption.  Absorbed Predheal transforms into an inactive form (6α-methylprednisolone-17-propionate) and is  primarily eliminated through the kidneys.

Indications and Usage:

• Suppress inflammatory and allergic skin reactions,  Predheal alleviates redness, thickening, edema, itching, and more.
• Effective for atopic dermatitis, eczema in children, contact eczema, and various eczema forms.

Contraindications:

• With limited experience with Predheal on the face and in children under 4 months, avoid using it in these cases.

Adverse Reactions:

• Possible side effects include skin thinning, visible blood vessels (telangiectasia), stretch marks, and acne-like conditions.
• Rarely, intensive topical use can lead to systemic side effects like adrenal suppression.

Dosage and Directions for Use:

• Apply Predheal thinly once daily to the affected area, as directed by your doctor.
• Treatment duration shouldn’t exceed 12 weeks for adults and 4 weeks for children.

Pregnancy and Breastfeeding:

• Predheal is not recommended during the first trimester of pregnancy.
• Risks outweigh potential benefits even when breastfeeding.
• Carefully evaluate both before starting treatment.

Overdosage:

Prolonged or improper use can lead to excessive dosing.  Stop using Predheal and seek medical attention immediately.

Drug Interactions:

While specific details are unavailable, exercise caution when starting or adjusting other medications while using Predheal.

Warning and Precautions:

Predheal is a potent steroid.  Avoid eye contact and prolonged use on large body areas.

Hypersensitivity reactions may occur.  Skin infections may worsen if applied to infected areas.

Storage Instructions:

Store below 30 °C, protected from light and moisture, and out of reach of children.

Presentation:

Predheal comes in 5g and 10g cream and ointment formulations.

Important Note:

For your safety and proper use, consult a healthcare professional before using Predheal and report any adverse reactions or concerns.