Apremist TABLETS

COMPOSITION:

Each filmcoated tablet contains: Apremist  (Apremilast): 30mg

 WHAT APREMIST IS AND WHAT IT IS USED FOR:

What Apremist is:

Apremilast contains the active substance apremilast, belonging to a group of medicines called phosphodiesterase 4 inhibitors These help reduce inflammation

What Apremist is used for:

Apremist is used to treat adults with the following
conditions:

•  Active Psoriatic Arthritis: When other medicines like DiseaseModifying Antirheumatic Drugs
  (DMARDs) are ineffective or not tolerated
•  Moderate to Severe Chronic Plaque Psoriasis: When other treatments like phototherapy or systemic
  therapy have not worked
•  Behçet’s Disease (BD): To treat mouth ulcers, a common symptom in people with this rare disease

How Apremist works:

Apremilast works by reducing the activity of an enzyme called phosphodiesterase 4 involved in the inflammation process By doing so, it helps control inflammation in psoriatic arthritis, psoriasis, and Behçet’s disease,
reducing associated signs and symptoms

 WHAT YOU NEED TO KNOW BEFORE YOU TAKE APREMIST:

 Do not take Apremist Tablet if:

•  You are allergic to Apremist Tablet or any of the other ingredients
•  You are pregnant or suspect pregnancy

 Warnings and precautions:

 Inform your doctor if you have depression or worsening depression with thoughts of suicide

Apremist contains lactose: Contact your doctor before taking if you have sugar intolerance

HOW TO TAKE APREMIST:

Always take Apremist as directed by your doctor The treatment initiation pack provides a gradual increase in dosage to reach the recommended daily dose of 60mg This ensures the correct dose is taken If you
have severe kidney problems, your doctor will adjust the dose

 How and when to take Apremist:

•  Swallow tablets whole with water
•  Take them with or without food
•  Take one tablet in the morning and one in the evening
• If your condition doesn’t improve after six months, consult your doctor
• If you take more Apremist: Seek medical attention immediately and take the medicine pack with you
• If you forget to take Apremist: Take the missed dose when you remember unless it’s almost time for your next dose Do not double the dose
• If you stop taking Apremist: Continue until your doctor advises otherwise

POSSIBLE SIDE EFFECTS:

Apremist may cause side effects, including:

•  Serious Side Effects: Notify your doctor of any behavior or mood changes, depression, suicidal thoughts, or behavior
•  Very Common Side Effects: Diarrhea, nausea, headaches, and upper respiratory tract infections
•  Common Side Effects: Cough, back pain, vomiting, fatigue, stomach pain, loss of appetite, frequent
  bowel movements, insomnia, indigestion, heartburn, and more
•  Uncommon Side Effects: Rash, itching, hives, and swelling, feeling anxious or nervous, weight decrease, memory issues, muscle pain, increased blood pressure
•  This is not a complete list of side effects Consult your doctor or pharmacist for more information
• Please consult your healthcare provider for more details and personalized guidance

 HOW TO STORE APREMIST Tablet:

Store Apremist in a cool, dry place below 30°C

 PRESENTATION:

Apremist is available in blister packs of 30 tablets

 Remember, this information does not replace professional medical advice Always consult your healthcare provider for guidance tailored to your specific needs