Apremist 56 Tablets | 30mg Tablets
Apremist 30mg by Crystolite contains apremilast 30mg, an oral phosphodiesterase-4 (PDE4) inhibitor prescribed for moderate-to-severe chronic plaque psoriasis, psoriatic arthritis and oral ulcers of Behcet's disease. By reducing intracellular inflammation, apremilast eases plaques, joint pain and swelling without immunosuppression. Pack of 56 film-coated tablets. Prescription required.
Pay in 3 Installments of
Rs.
1800
Apremist 56 Tablets | 30mg Tablets
Description
Apremist TABLETS
COMPOSITION:
Each filmcoated tablet contains: Apremist (Apremilast): 30mg
WHAT APREMIST IS AND WHAT IT IS USED FOR:
What Apremist is:
Apremilast contains the active substance apremilast, belonging to a group of medicines called phosphodiesterase 4 inhibitors These help reduce inflammation
What Apremist is used for:
Apremist is used to treat adults with the following
conditions:
- Active Psoriatic Arthritis: When other medicines like DiseaseModifying Antirheumatic Drugs
(DMARDs) are ineffective or not tolerated - Moderate to Severe Chronic Plaque Psoriasis: When other treatments like phototherapy or systemic
therapy have not worked - Beh çet's Disease (BD): To treat mouth ulcers, a common symptom in people with this rare disease
How Apremist works:
Apremilast works by reducing the activity of an enzyme called phosphodiesterase 4 involved in the inflammation process By doing so, it helps control inflammation in psoriatic arthritis, psoriasis, and Beh çet's disease,
reducing associated signs and symptoms
WHAT YOU NEED TO KNOW BEFORE YOU TAKE APREMIST:
Do not take Apremist Tablet if:
- You are allergic to Apremist Tablet or any of the other ingredients
- You are pregnant or suspect pregnancy
Warnings and precautions:
Inform your doctor if you have depression or worsening depression with thoughts of suicide
Apremist contains lactose: Contact your doctor before taking if you have sugar intolerance
HOW TO TAKE APREMIST:
Always take Apremist as directed by your doctor The treatment initiation pack provides a gradual increase in dosage to reach the recommended daily dose of 60mg This ensures the correct dose is taken If you
have severe kidney problems, your doctor will adjust the dose
How and when to take Apremist:
- Swallow tablets whole with water
- Take them with or without food
- Take one tablet in the morning and one in the evening
- If your condition doesn't improve after six months, consult your doctor
- If you take more Apremist: Seek medical attention immediately and take the medicine pack with you
- If you forget to take Apremist: Take the missed dose when you remember unless it's almost time for your next dose Do not double the dose
- If you stop taking Apremist: Continue until your doctor advises otherwise
POSSIBLE SIDE EFFECTS:
Apremist may cause side effects, including:
- Serious Side Effects: Notify your doctor of any behavior or mood changes, depression, suicidal thoughts, or behavior
- Very Common Side Effects: Diarrhea, nausea, headaches, and upper respiratory tract infections
- Common Side Effects: Cough, back pain, vomiting, fatigue, stomach pain, loss of appetite, frequent
bowel movements, insomnia, indigestion, heartburn, and more - Uncommon Side Effects: Rash, itching, hives, and swelling, feeling anxious or nervous, weight decrease, memory issues, muscle pain, increased blood pressure
- This is not a complete list of side effects Consult your doctor or pharmacist for more information
- Please consult your healthcare provider for more details and personalized guidance
HOW TO STORE APREMIST Tablet:
Store Apremist in a cool, dry place below 30 °C
PRESENTATION:
Apremist is available in blister packs of 30 tablets
Remember, this information does not replace professional medical advice Always consult your healthcare provider for guidance tailored to your specific needs
Usage & Benefits
Oral PDE4 inhibitor for chronic plaque psoriasis
Effective in psoriatic arthritis joint pain and swelling
Non-biologic and non-immunosuppressive alternative
No routine baseline TB or lab screening required
Useful for Behcet's oral ulcers and scalp psoriasis
56-tablet pack provides 4 weeks maintenance after titration
How To Use
1. Start with a 5-day titration pack as directed by your dermatologist or rheumatologist.
2. Maintenance dose is typically one 30mg tablet twice daily, morning and evening, about 12 hours apart.
3. Swallow whole with water; food does not significantly affect absorption.
4. Diarrhoea, nausea or headache often occur in the first 2 weeks then settle; stay hydrated.
5. Report new or worsening depression, mood changes or suicidal thoughts to your doctor immediately.
6. Notify your doctor if you experience significant unexplained weight loss; ongoing weight monitoring is advised.
FAQs
Do I need a prescription?
Yes. Apremilast is a prescription-only specialist medication in Pakistan.
How long until psoriasis improves?
Many patients see improvement within 16 weeks of consistent twice-daily dosing.
Does it suppress the immune system?
No. Apremilast is non-immunosuppressive and does not require routine TB or hepatitis screening.
What about mood changes?
Apremilast can increase risk of depression and suicidal thoughts in some patients. Discuss any psychiatric history with your doctor and report mood symptoms promptly.
Why is the first pack titrated?
Gradual dose ramp-up over 5 days reduces nausea and diarrhoea, improving tolerability.
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