Makazi (Azithromycin): Treating Bacterial Infections

Composition:

MAKAZI CAPSULES 250mg Capsules:
Each capsule contains Azithromycin (as dihydrate) equivalent to 250mg
Azithromycin

Description:

MAKAZI CAPSULES is a semisynthetic antibiotic belonging to the
azalide group It's an antibacterial agent that inhibits protein synthesis,
classified under the antibiotics pharmacological group The molecular weight of
Azithromycin is 78500

Pharmacodynamic Properties:

Azithromycin is a macrolide antibiotic that inhibits
bacterial protein synthesis by binding to the ribosomal 50s subunit and
inhibiting peptide translocation It concentrates in phagocytes and contributes
to drug distribution in inflamed tissues

Microbiological Coverage:

Makazi is effective against various bacteria, including
Staphylococcus aureus, Staphylococcus pneumoniae, Herophilus influenzae,
Neisseria gonorrhoeae, Chlamydia pneumonia, and more It's important to note
that some bacterial strains may be resistant to Azithromycin

Therapeutic Indications:

Makazi is prescribed for the treatment of:

• Acute bacterial
  sinusitis
• Community acquired
  pneumonia
• Pharyngitis/tonsillitis
• Uncomplicated skin
  and skin structure infections
• Genital ulcer
  diseases in men
• Acute bacterial
  exacerbations of chronic obstructive pulmonary disease

Dosage and Method of Administration:

Makazi should be taken at least 1 hour before or 2 hours
after a meal The dosage varies based on the condition and its severity

Precautions:

• Makazi is not
  recommended in patients with severe liver disease or hypersensitivity to
  Azithromycin
• Caution is advised in
  patients with renal impairment, and it should not be used in patients with
  severe renal dysfunction
• It should be used
  with caution in patients at risk for prolonged cardiac repolarization
• The drug should only
  be used when necessary during pregnancy or lactation

Interactions:

Azithromycin may interact with various drugs, including
aluminum based antacids, cyclosporine, digoxin, and more Consult a healthcare provider
for potential interactions

Side Effects:

Common side effects include gastrointestinal symptoms like
diarrhea, nausea, abdominal pain, and vomiting Less frequently, it may cause
allergic reactions, cardiovascular issues, nervous system problems, skin
reactions, and more

Overdose:

Symptoms of overdose may include reversible hearing loss,
severe nausea, vomiting, and diarrhea Treatment involves administration of
medicinal charcoal and symptomatic support

Storage Conditions:

Store below 30 °C, protect from sunlight and moisture, and
keep out of reach of children

How Supplied:

Makazi is available in capsule and tablet forms in packs of
10

Usage and Benefits of Makazi (Azithromycin) 250mg Capsules

• Treats Bacterial Infections: Makazi is highly effective in treating a range of bacterial infections including sinusitis, pneumonia, and pharyngitis.
• Broad-Spectrum Antibiotic: It works against various bacteria like Staphylococcus aureus, Neisseria gonorrhoeae, and Chlamydia pneumoniae.
• Convenient Dosage: Makazi’s once-daily dose allows for easy compliance, making it a convenient option for patients.
• Effective for Respiratory and Skin Conditions: It helps in treating respiratory infections, skin infections, and even chronic bacterial conditions like COPD exacerbations.
• Well-Tolerated: Most patients tolerate Azithromycin well, with fewer side effects compared to other antibiotics.

How to Use Makazi (Azithromycin) 250mg Capsules

Makazi is taken orally. It should be consumed at least one hour before or two hours after a meal to ensure maximum absorption. Follow the dosage instructions provided by your doctor. The dosage may vary depending on the condition being treated. Typically, the capsule should be swallowed whole with water.

Note: Do not chew or crush the capsule. Always complete the full course of treatment as prescribed by your healthcare provider, even if symptoms improve, to ensure the infection is fully treated.

FAQs for Makazi (Azithromycin) 250mg Capsules

1. What is Makazi (Azithromycin) used for?

Makazi is a broad-spectrum antibiotic used to treat various bacterial infections. It is effective against conditions such as acute bacterial sinusitis, community-acquired pneumonia, pharyngitis/tonsillitis, uncomplicated skin infections, genital ulcer diseases in men, and acute bacterial exacerbations of chronic obstructive pulmonary disease (COPD).

2. How should I take Makazi capsules?

Makazi should be taken orally, at least one hour before or two hours after a meal. The dosage will vary depending on the infection being treated. Always follow the dosage instructions provided by your healthcare provider.

3. Are there any common side effects of Makazi?

Yes, some common side effects of Makazi include gastrointestinal symptoms like diarrhea, nausea, abdominal pain, and vomiting. Less frequently, it may cause allergic reactions, cardiovascular issues, nervous system problems, and skin reactions. If you experience any of these, consult your healthcare provider.

4. What precautions should I take when using Makazi?

Makazi should be used with caution in patients with renal impairment, liver disease, or those at risk for prolonged cardiac repolarization. It is not recommended during pregnancy unless necessary, and it should not be used during breastfeeding unless advised by a doctor. Always discuss your medical history with your healthcare provider before starting the medication.

5. What should I do if I overdose on Makazi?

In case of overdose, symptoms may include reversible hearing loss, severe nausea, vomiting, and diarrhea. Treatment usually involves the administration of medicinal charcoal and supportive care. If you suspect an overdose, seek immediate medical attention.