Avate Cream 10g (Methylprednisolone Aceponate 0.1%)
Avate Cream 10g by Crystolite Pharmaceuticals — a prescription-only topical corticosteroid cream containing Methylprednisolone Aceponate 0.1% w/w. Indicated for eczema (endogenous, contact, vulgar, degenerative, dyshidrotic) and psoriasis in adults and children. Prescription required. Maximum duration: 12 weeks in adults, 4 weeks in children. Use as directed by your dermatologist. For external use only.
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Avate Cream 10g (methylprednisolone Aceponate 0.1%)
Description
Avate: Dermatological Solution for Eczema and Psoriasis
Avate is a potent dermatological solution containing Methylprednisolone Aceponate (0.1% w/w), a synthetic corticosteroid. With its specialized formulation, Avate provides effective treatment for a variety of skin conditions, including eczema and psoriasis, in both adults and children.
Composition
- Active Ingredient: Methylprednisolone Aceponate (0.1% w/w)
- Form: Available as cream and ointment in a 10gm plastic tube
Description
Avate is a revolutionary white crystalline powder with solubility in methylene chloride, acetone, and ethyl acetate. Its molecular formula, C27H36O7, and molecular weight of 472.58 highlight its synthetic corticosteroid nature, making it highly effective for dermatological treatments.
Indications
Avate is designed to treat a variety of skin conditions, including:
-
Eczema:
- Endogenous eczema
- Contact eczema
- Vulgar eczema
- Degenerative eczema
- Dyshidrotic eczema
- Psoriasis: Suitable for adult and pediatric use
Pharmacological Action
Avate Cream works by binding to intracellular glucocorticoid receptors, delivering:
- Anti-inflammatory effects to reduce swelling and redness
- Antipruritic properties to alleviate itching
- Vasoconstrictive action to minimize blood vessel dilation and inflammation
Contraindications
Avate should not be used in the following conditions:
- Viral diseases (e.g., herpes, varicella)
- Tuberculous or syphilitic skin processes
- Post-vaccination skin reactions
- Rosacea, acne vulgaris, or perioral dermatitis when applied to the face
- Hypersensitivity: Avoid use if allergic to Methylprednisolone Aceponate
Adverse Reactions
Localized symptoms may include:
- Itching
- Burning
- Erythema
Rare effects:
- Atrophic skin changes with prolonged use
Dosage and Administration
- Application: Apply a thin layer of Avate once daily to affected areas.
-
Duration:
- Adults: Up to 12 weeks
- Children: Up to 4 weeks
Precautions
- Avoid prolonged use: Especially in children, to prevent adrenal suppression.
- Prevent contact: Keep away from eyes, mouth, and mucous membranes.
- Infections: Discontinue use in spreading infections or hypersensitivity reactions.
Presentation
Avate is packaged in a 10gm plastic tube, offering convenience and precise application.
Conclusion
In summary, Avate provides a reliable solution for managing eczema and psoriasis with its anti-inflammatory, antipruritic, and vasoconstrictive properties. However, it is essential to carefully consider contraindications, adhere to recommended dosages, and monitor for potential adverse effects for safe and effective use. By following these guidelines, Avate can help restore healthy skin and improve quality of life.
Usage & Benefits
- Contains Methylprednisolone Aceponate 0.1% w/w — a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties
- Indicated for eczema (endogenous, contact, vulgar, degenerative, dyshidrotic) and psoriasis under dermatologist supervision
- Reduces skin swelling, redness, and itching as prescribed by a qualified physician
- Suitable for both adult and pediatric patients under medical supervision with duration limits
- Available in 10g plastic tube by Crystolite Pharmaceuticals
- Explore derma.pk's full eczema treatment range and psoriasis care collection
- Browse itching relief products and redness treatments
- Note: Prescription required. All benefits apply under dermatologist supervision. Do not self-medicate.
How To Use
Apply as directed by your dermatologist or doctor. Do not self-medicate.
1. Clean and gently dry the affected skin area before applying.
2. Apply a thin layer of Avate Cream once daily to the affected area as prescribed.
3. Do not exceed recommended duration: maximum 12 weeks in adults, 4 weeks in children.
4. Avoid contact with eyes, mouth, and mucous membranes.
5. Do not apply to face for rosacea, acne vulgaris, or perioral dermatitis conditions.
6. Discontinue use and consult your doctor if spreading infection or hypersensitivity develops.
7. Especially in children, monitor for signs of adrenal suppression with prolonged use.
8. Store at room temperature in the 10g plastic tube, away from heat and sunlight. Keep out of reach of children.
FAQs
Do I need a prescription for Avate Cream?
Yes — this is a prescription-only topical corticosteroid medication. Always use under dermatologist supervision with a valid prescription. Do not self-medicate.
What skin conditions is Avate Cream used for?
Under dermatologist supervision, Avate Cream is indicated for endogenous eczema, contact eczema, vulgar eczema, degenerative eczema, dyshidrotic eczema, and psoriasis in both adults and children.
How long can Avate Cream be used?
Maximum 12 weeks in adults and 4 weeks in children. Do not exceed the prescribed duration as prolonged use of topical corticosteroids can cause adrenal suppression and skin atrophy.
Can Avate Cream be used on the face?
It must not be applied to the face for rosacea, acne vulgaris, or perioral dermatitis. Only use on the face if specifically prescribed by your dermatologist for approved conditions.
What are the contraindications for Avate Cream?
Avate should not be used in viral skin diseases (herpes, varicella), tuberculous or syphilitic skin conditions, post-vaccination skin reactions, or in cases of hypersensitivity to methylprednisolone aceponate.
Is Avate Cream safe for children?
Under qualified dermatologist supervision only, with maximum 4 weeks of use in children. Prolonged use in children may cause adrenal suppression. Follow your dermatologist's instructions strictly.
Where can I find more skin condition treatments at derma.pk?
Explore our fungal & eczema treatments, rash treatments, and essential health products.
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