Empaa M XR 25/1000mg Tablet
- Combination of Empagliflozin 25mg (higher-dose SGLT2 inhibitor) and Metformin XR 1000mg (biguanide).
- Higher empagliflozin dose provides stronger renal glucose excretion and greater LDL reduction.
- Extended-release metformin for sustained once-daily glycaemic control.
- Cardiovascular and renal protection; lowers HbA1c more than 12.5mg empagliflozin.
- Prescription medicine — use under physician supervision. Not for eGFR <45.
Pay in 3 Installments of
Rs.
268
Empaa M Xr 25/1000mg Tablet
Description
Empaa M XR 25/1000mg Tablet
Prescription Required. Available at Derma.pk with valid prescription.
Empaa M XR 25/1000mg is a fixed-dose extended-release combination of Empagliflozin 25mg (SGLT2 inhibitor) and Metformin XR 1000mg (biguanide) for adults with type 2 diabetes mellitus who require stronger glycaemic control. The higher empagliflozin dose (25mg vs 12.5mg) provides more pronounced renal glucose excretion and enhanced weight-neutral blood sugar reduction. Metformin XR suppresses hepatic glucose production and improves insulin sensitivity with a favourable tolerability profile.
Empagliflozin at 25mg also delivers significant cardiovascular and renal benefits, including reduced risk of major adverse cardiovascular events and slowing of chronic kidney disease progression. Extended-release delivery ensures once-daily dosing with consistent 24-hour coverage. Not recommended for eGFR below 45 mL/min/1.73m².
How to Buy Empaa M XR 25/1000mg at Derma.pk
Order from Derma.pk with valid prescription. Contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
- Stronger Glucose Excretion: 25mg empagliflozin provides greater urinary glucose loss and more pronounced HbA1c reduction than the 12.5mg dose.
- Extended-Release Convenience: Metformin XR 1000mg enables consistent once-daily dosing with reduced gastrointestinal side effects.
- Cardiovascular Protection: Empagliflozin at 25mg demonstrated significant reduction in cardiovascular death, non-fatal MI, and hospitalisation for heart failure in the EMPA-REG OUTCOME trial.
- Renal Protection: Slows diabetic kidney disease progression and reduces risk of end-stage renal disease.
- Weight Management: SGLT2 inhibition promotes modest, sustained weight loss without causing hypoglycaemia when used as monotherapy or with metformin.
How To Use
1. Use as directed by your physician.
2. Typically taken once daily with the evening meal.
3. Swallow whole — do not crush, split, or chew the extended-release tablet.
4. Maintain regular blood glucose and kidney function monitoring.
5. Do not discontinue without consulting your doctor.
FAQs
How is Empaa M XR 25/1000mg different from the 12.5/1000mg version?
This formulation contains a higher empagliflozin dose (25mg vs 12.5mg), providing more pronounced renal glucose excretion and stronger glycaemic control for patients needing dose escalation.
Do I need a prescription?
Yes — this is a prescription-only medicine that must be taken under medical supervision.
Can this medicine be used in patients with heart disease?
Yes, it is particularly beneficial for type 2 diabetes patients with established cardiovascular disease, given empagliflozin's proven cardioprotective effects.
Is it safe in chronic kidney disease?
Not recommended if eGFR is below 45 mL/min/1.73m². Kidney function must be checked before prescribing.
Where can I buy this in Pakistan?
Available at Derma.pk with a valid prescription. Contact sales@derma.pk or WhatsApp +92-320-5999650.
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