About Glucomet Plus 5/500mg Tablets

Glucomet Plus 5/500mg Tablets are a prescription-only combination of Glibenclamide 5mg (a sulfonylurea) and Metformin Hydrochloride 500mg (a biguanide), providing dual-action control of blood glucose in adults with type 2 diabetes mellitus. Glibenclamide stimulates insulin release from pancreatic beta cells; Metformin reduces hepatic glucose production, lowers intestinal glucose absorption, and improves peripheral insulin sensitivity — together achieving better glycaemic control than either agent alone.

Glibenclamide carries the highest hypoglycaemia risk among sulfonylureas. Monitor blood glucose regularly, never skip meals, and carry a fast-acting sugar source. Prescription required — do not self-medicate. Long-term use requires periodic monitoring of renal and hepatic function. Not suitable for type 1 diabetes, severe kidney disease, or hepatic impairment.

Browse our full general medicines collection or see all tablets and capsules available at Derma.pk with fast delivery across Lahore, Karachi, and Islamabad.

Key Benefits

• Dual-mechanism glycaemic control: insulin secretion + hepatic glucose reduction
• Reduces fasting and post-meal blood sugar levels
• Helps prevent long-term diabetic complications (neuropathy, nephropathy, retinopathy)
• Supports weight-neutral diabetes management (Metformin component)
• Comprehensive single-tablet convenience for combination therapy

How to Use

1. Take exactly as prescribed by your physician — never adjust dose without medical advice.
2. Swallow tablets whole with water during or immediately after a meal to reduce GI side effects.
3. Take at the same time each day to maintain stable blood glucose levels.
4. Monitor blood glucose as directed; watch for hypoglycaemia symptoms (dizziness, sweating, shakiness) — seek prompt medical attention if severe.

Frequently Asked Questions

Q: Is Glucomet Plus 5/500mg available without a prescription?

A: No. Glucomet Plus contains Glibenclamide, a sulfonylurea that must be used under physician supervision. A valid prescription is required.

Q: What is the hypoglycaemia risk with Glibenclamide?

A: Glibenclamide has the highest hypoglycaemia risk among sulfonylureas. Skipping meals, excessive exercise, or alcohol can trigger severe low blood sugar. Always carry glucose tablets or juice.

Q: Can I take Glucomet Plus if I have kidney disease?

A: No — both Glibenclamide and Metformin are contraindicated in significant renal impairment (eGFR < 30 mL/min). Consult your doctor for alternative therapy.