Sitaphage 50/1000mg Tablets (Sitagliptin + Metformin) for Type 2 Diabetes
Sitaphage 50/1000mg is a prescription dual-action tablet combining sitagliptin (DPP-4 inhibitor) and metformin HCl for type 2 diabetes management. It reduces blood glucose through complementary mechanisms — incretin enhancement and reduced hepatic glucose output. A valid prescription is required.
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Sitaphage 50/1000mg Tablets (sitagliptin + Metformin) for Type 2 Diabetes
Description
Sitaphage 50/1000mg Tablets — Sitagliptin & Metformin for Type 2 Diabetes
Sitaphage 50/1000mg is a fixed-dose combination tablet containing sitagliptin 50mg (a DPP-4 inhibitor) and metformin HCl 1000mg (a biguanide), prescribed for comprehensive glycaemic management in adults with type 2 diabetes mellitus.
Sitagliptin inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), prolonging incretin hormone activity to stimulate glucose-dependent insulin release and suppress glucagon. Metformin reduces hepatic glucose production, improves peripheral insulin sensitivity, and enhances cellular glucose uptake — providing complementary dual-action glycaemic control.
This medicine requires a valid prescription from a licensed physician.
Indications
- Type 2 diabetes mellitus — when diet and exercise alone are insufficient
- Adjunct therapy when sitagliptin or metformin monotherapy does not achieve adequate control
- May be used in combination with sulfonylureas or insulin under physician supervision
Important Information
- Not for use in type 1 diabetes or diabetic ketoacidosis
- Withhold before iodinated contrast procedures — risk of lactic acidosis
- Monitor renal function periodically during treatment
- Report symptoms of pancreatitis (severe abdominal pain) to physician immediately
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Usage & Benefits
- Dual-action glycaemic control via DPP-4 inhibition and biguanide mechanisms
- Sitagliptin stimulates glucose-dependent insulin release and suppresses glucagon
- Metformin reduces hepatic glucose production and improves insulin sensitivity
- Suitable as initial or adjunct therapy in type 2 diabetes management
- Once-daily dosing supports treatment adherence
How To Use
Take Sitaphage 50/1000mg once daily with food as directed by your physician. Swallow the tablet whole — do not crush or chew. Monitor blood glucose regularly. If combining with insulin or sulfonylurea, your physician may adjust doses to minimise hypoglycaemia risk. Consult physician before stopping therapy.
FAQs
What is Sitaphage 50/1000mg used for?
Sitaphage 50/1000mg combines sitagliptin and metformin to manage blood glucose in adults with type 2 diabetes mellitus. It is indicated when diet, exercise, or monotherapy alone do not achieve adequate glycaemic control.
Is a prescription required for Sitaphage?
Yes. Sitaphage is a prescription-only medicine. Please consult a licensed physician before use.
How does Sitaphage 50/1000mg differ from Sitaphage 50/500mg?
Sitaphage 50/1000mg contains a higher dose of metformin (1000mg) compared to Sitaphage 50/500mg (500mg). Your physician will determine the appropriate strength based on your clinical needs.
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