Spiromide Tablets 40mg - Overview

Spiromide Tablets 40mg are a combination medication used to treat heart failure, oedema, and fluid retention associated with kidney disease and liver disease. These tablets contain Furosemide, a potent diuretic, and Spironolactone, an aldosterone antagonist that works by increasing sodium excretion while reducing potassium loss.

• Furosemide is a short-acting diuretic that starts working quickly and helps remove excess fluid from the body. It is particularly effective for conditions like heart failure and chronic kidney disease.

• Spironolactone is used to balance electrolytes, preventing the loss of potassium, which can often occur with the use of other diuretics. It is known for its slow and prolonged action, providing sustained relief for fluid retention and heart failure.

How Do Spiromide Tablets Work?

• Furosemide helps to reduce fluid buildup in the body by increasing urine production. This process is essential in heart failure patients who experience fluid retention, reducing the strain on the heart and lowering blood pressure.

• Spironolactone works by blocking aldosterone, a hormone that increases sodium and water retention in the kidneys. By inhibiting this hormone, Spironolactone prevents fluid retention, which helps treat oedema and heart failure symptoms.

Together, Furosemide and Spironolactone work synergistically to alleviate fluid retention, reduce swelling, and lower blood pressure, providing relief from conditions like heart failure, oedema, and liver disease.

Indications for Use

Spiromide Tablets 40mg are primarily used in the treatment of:

• Heart failure, especially in patients who experience fluid retention and oedema.

• Oedema associated with chronic liver disease, kidney disease, or heart failure.

• To help manage secondary hyperaldosteronism, a condition where excessive aldosterone causes fluid retention.

Possible Side Effects

Common side effects may include:

• Dizziness, headache, and nausea.

• Low blood pressure, especially when standing up (orthostatic hypotension).

• Abdominal discomfort, diarrhea, or constipation.

In rare cases, severe reactions include:

• Electrolyte imbalances (low potassium or sodium levels).

• Kidney dysfunction or liver issues.

• Rashes, swelling, and breathing problems.

Consult your doctor if any of these symptoms worsen or persist.

Drug Interactions

• ACE inhibitors like ramipril and enalapril.

• NSAIDs such as ibuprofen and aspirin may reduce the effectiveness of Spiromide.

• Potassium supplements and other diuretics like triamterene or amiloride can lead to dangerous increases in potassium levels.

Precautions and Warnings

• Monitor kidney and liver function regularly during treatment.

• Spiromide Tablets should be used with caution in patients with kidney or liver disease.

• Frequent electrolyte checks are necessary, particularly in patients with high blood pressure or hypotension.

• Avoid using Spiromide Tablets if pregnant or planning to become pregnant without consulting a healthcare provider.

Storage and Handling

• Store in a cool, dry place away from direct sunlight.

• Keep out of reach of children.

• Use within the expiry date provided on the packaging.
  

  For more information, contact us at:

  • Email: sales@derma.pk

  • WhatsApp: +92-320-5999650