Imutrex (Methotrexate) 25mg tablets, an essential cytotoxic antimetabolite, play a pivotal role in combating malignant tissue with high cell turnover. By irreversibly binding with dihydrofolate reductase and inhibiting nucleic acid synthesis, Imutrex effectively hinders cell division.
Description and Action
Imutrex functions as a folic acid antagonist. This potent medication finds utility in managing various malignant diseases, including acute lymphoblastic leukemia, choriocarcinoma, and psoriasis.
Dosage Guidelines
In adult ALL, doctors recommend 33mg daily per square meter of skin, taken with prednisolone. The maintenance dosage is typically 20-30 mg/M2 twice weekly.
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