Amodip Plus Tablets 5mg/12.5mg — Amlodipine & Hydrochlorothiazide for Hypertension
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Description
Amodip Plus Tablets 5mg/12.5mg — Dual-Action Antihypertensive
Amodip Plus Tablets combine Amlodipine 5mg (dihydropyridine calcium channel blocker) and Hydrochlorothiazide 12.5mg (thiazide diuretic) in a single tablet for patients requiring combination antihypertensive therapy. This dual mechanism provides additive blood pressure reduction: amlodipine causes vasodilation while HCTZ promotes sodium and water excretion — together achieving better BP control than either agent alone.
An additional benefit of adding HCTZ is that it can partially counteract the peripheral oedema (ankle swelling) that may occur with amlodipine monotherapy, improving tolerability for many patients.
Indications
- Hypertension inadequately controlled by monotherapy
- Hypertensive patients who experience oedema with CCB monotherapy
- Step-up therapy from single-agent antihypertensives
Key Clinical Features
- Dual mechanism: CCB vasodilation + thiazide diuresis
- HCTZ may partially offset CCB-associated ankle oedema
- Once-daily fixed-dose combination — improves adherence
- Monitor electrolytes (sodium, potassium), glucose, and uric acid with HCTZ
- Use with caution in gout — HCTZ raises uric acid levels
Important Safety Information
Prescription Only (Rx). Strictly as prescribed by your doctor. Monitor electrolytes periodically. Contraindicated in severe renal impairment and anuria. Caution in gout and diabetes.
How to Buy from Derma.pk
- Prescription required for dispensing
- Nationwide delivery — Lahore, Karachi, Islamabad & all Pakistan
- Cash on delivery available
Browse all hypertension medicines and prescription medicines on Derma.pk.
Usage & Benefits
- Dual-mechanism BP control: CCB vasodilation + thiazide diuresis
- More effective hypertension management than monotherapy for many patients
- HCTZ may partially counteract amlodipine-induced ankle oedema
- Fixed-dose combination — simplifies regimen and improves adherence
- Once-daily dosing for consistent blood pressure control
How To Use
As prescribed by your doctor. Prescription only (Rx). Take once daily as directed. Monitor electrolytes periodically. Do not stop or adjust the dose without medical advice.
FAQs
What is Amodip Plus used for?
Amodip Plus combines amlodipine 5mg and hydrochlorothiazide 12.5mg for hypertension that is not adequately controlled by a single agent, or where combination therapy offers better tolerability.
Why is HCTZ combined with amlodipine in Amodip Plus?
Hydrochlorothiazide adds a diuretic mechanism to amlodipine's vasodilation, providing additive BP reduction. HCTZ can also partially counteract the ankle swelling sometimes caused by amlodipine alone.
What should be monitored with Amodip Plus?
Periodic electrolyte monitoring (sodium, potassium) is recommended with HCTZ. Also monitor blood glucose and uric acid, especially in patients with diabetes or gout risk.
Can I buy Amodip Plus online in Pakistan?
Yes, Amodip Plus Tablets are available on Derma.pk with nationwide delivery. A valid prescription is required.
