Anifed Retard 20mg Tablet – Nifedipine Extended Release for Hypertension
- Nifedipine 20mg in extended-release (retard) formulation.
- Dihydropyridine calcium channel blocker for hypertension & angina.
- Gradual release maintains consistent blood pressure control.
- Do not crush or chew — swallow whole to preserve ER matrix.
- Prescription required. Available at Derma.pk with nationwide delivery.
Pay in 3 Installments of
Rs.
143
Anifed Retard 20mg Tablet – Nifedipine Extended Release for Hypertension
Description
Anifed Retard 20mg Tablet – Nifedipine Extended-Release for Hypertension & Angina
Anifed Retard 20mg Tablet contains Nifedipine 20mg in an extended-release (retard) formulation — a dihydropyridine calcium channel blocker widely prescribed for the management of hypertension (high blood pressure) and chronic stable angina. The extended-release matrix ensures a gradual, steady release of Nifedipine over 12–24 hours, maintaining consistent blood pressure control and avoiding the rapid peak-plasma effects associated with immediate-release Nifedipine.
Nifedipine works by blocking L-type voltage-dependent calcium channels in vascular smooth muscle, causing vasodilation of peripheral arteries and coronary vessels. This reduces peripheral vascular resistance, lowers blood pressure, and improves oxygen delivery to the myocardium — reducing the frequency and severity of anginal episodes. It also helps prevent stroke, heart attack, and hypertensive kidney damage through sustained blood pressure control.
Important Clinical Notes
- Do not crush, chew, or split the tablet — the extended-release matrix must remain intact
- Do not stop abruptly — withdrawal may cause rebound hypertension or angina
- Avoid grapefruit juice during therapy (CYP3A4 interaction)
- Prescription required — to be used under physician supervision only
For all blood pressure medicines, browse our Anti-Hypertensive collection. See also our range of Essential Health Products for cardiovascular support.
How to Buy Anifed Retard 20mg from Derma.pk
- Order at Derma.pk — reliable delivery nationwide across Pakistan.
- Prescription required — share via WhatsApp: 0320-5999650 or email: sales@derma.pk.
Usage & Benefits
- Lowers high blood pressure effectively through peripheral vasodilation.
- Prevents chronic angina episodes by improving coronary blood flow.
- Reduces risk of stroke, heart attack, and hypertensive kidney damage.
- Extended-release formula avoids rapid blood pressure fluctuations.
- Reduces cardiac workload — beneficial in hypertension with angina.
How To Use
1. Take exactly as prescribed by your doctor — do not self-adjust the dose.
2. Swallow whole with water — do not crush, chew, or split (destroys ER matrix).
3. Take at the same time each day — with or without food.
4. Avoid grapefruit or grapefruit juice during therapy (increases Nifedipine levels).
5. Do not stop abruptly — gradual discontinuation under medical supervision only.
FAQs
What is Anifed Retard used for?
It treats high blood pressure (hypertension) and chronic stable angina (chest pain) using Nifedipine, an extended-release calcium channel blocker.
What does "Retard" mean on the packaging?
"Retard" indicates an extended-release (ER/XL) formulation — the tablet releases Nifedipine gradually over 12–24 hours for steady, sustained blood pressure control.
Can I cut or crush Anifed Retard?
No — crushing or splitting destroys the extended-release matrix, causing the full dose to release rapidly, which can cause dangerous blood pressure drops. Always swallow whole.
Why should I avoid grapefruit?
Grapefruit inhibits the CYP3A4 enzyme that metabolises Nifedipine, potentially causing higher drug levels and excessive blood pressure lowering.
Does Anifed Retard require a prescription?
Yes — it is a prescription-only medicine. Share your prescription via WhatsApp: 0320-5999650 or email: sales@derma.pk.



