AVATE OINTMENT (METHYLPREDNISOLONE ACEPONATE) 10gram
AVATE OINTMENT (Methylpredisolone Aceponate 0.1% w/w by Crystolite Pharma)
Contains 0.1% Methylprednisolone Aceponate, a synthetic corticosteroid
Used topically for eczema and psoriasis treatment in adults and children
Provides anti-inflammatory, antipruritic, and vasoconstrictive effects
Avoid in viral skin diseases, tuberculosis, syphilis, and certain facial skin conditions. Do not use if hypersensitive to ingredients
Apply thin layer once daily; treatment duration varies for adults and children

Avate Ointment
Avate Ointment, a product developed by Cristate Pharmaceuticals, offers targeted relief for various skin conditions. It contains 0.1% w/w of Methylprednisolone Aceponate as its active ingredient. This synthetic corticosteroid is solvable in specific solvents and exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties.
Indication:
Indicated for eczema and psoriasis in both adults and children, Avate Ointment's mechanism involves binding to intracellular glucocorticoid receptors, triggering therapeutic effects. However, it's contraindicated in cases of viral diseases, tuberculosis, and hypersensitivity reactions to its components.
Direction for Use:
Cleanse: Begin by cleaning the affected skin area with a mild, fragrance-free cleanser. Pat the skin dry gently before applying Avate Ointment.
Apply Thin Layer: Use a small amount of Avate Ointment and apply it thinly over the affected area. Avoid excessive application to ensure effective results.
Massage Gently: Massage the ointment into the skin with gentle circular motions until it is evenly distributed and absorbed.
Frequency: Follow the recommended frequency of use, applying Avate Ointment once daily for the prescribed duration. Adhere to the treatment plan provided by your healthcare professional.
Observe and Consult: Monitor the skin for any adverse reactions such as itching, burning, or redness. If you notice any concerning reactions or have questions about the application, consult your healthcare provider promptly.
Dosage:
Potential adverse reactions may include localized symptoms like itching, burning, and erythema, while prolonged use might lead to atrophic changes and pigmentation variations. It's typically applied thinly once daily for up to 12 weeks in adults and 4 weeks in children.
Conclusion:
Caution is necessary during prolonged therapy to prevent adrenal suppression, and avoiding contact with sensitive areas is advised. Avate Ointment is available in a 10-gram plastic tube. Remember, it's crucial to seek professional medical guidance for personalized use, as this overview doesn't substitute proper medical advice.
Usage and Benefits of Avate Ointment
- Effective for Eczema and Psoriasis: Avate Ointment is designed to treat various forms of eczema and psoriasis, reducing inflammation, itching, and redness.
- Anti-Inflammatory Action: The Methylprednisolone Aceponate in Avate reduces swelling and irritation, helping restore skin health and comfort.
- Relieves Itching: Avate has antipruritic properties that alleviate the discomfort of itching caused by skin conditions like eczema and psoriasis.
- Vasoconstrictive Effect: It minimizes blood vessel dilation, helping reduce redness and promoting faster healing of the affected skin areas.
- Gentle for Long-Term Use: When used as directed, Avate Ointment is suitable for both adults and children, offering effective relief with minimal side effects.
How to Use Avate Ointment
Follow these simple steps for effective use of Avate Ointment:
- Cleanse the Area: Gently clean the affected skin area using a mild, fragrance-free cleanser and pat it dry.
- Apply a Thin Layer: Squeeze a small amount of Avate Ointment onto your fingertip and apply a thin layer to the affected area.
- Massage Gently: Massage the ointment into the skin using gentle circular motions until it is absorbed.
- Frequency: Apply once daily, or as directed by your healthcare provider. Avoid excessive application to ensure effective results.
Monitor for any adverse reactions like redness, itching, or burning. If these persist, consult your healthcare provider for guidance.
Frequently Asked Questions (FAQs) about Avate Ointment
1. What is Avate Ointment used for?
Avate Ointment contains 0.1% Methylprednisolone Aceponate and is used to treat skin conditions like eczema and psoriasis. It works by reducing inflammation, itching, and redness, providing relief for both adults and children.
2. How does Avate Ointment work?
Avate Ointment works by binding to glucocorticoid receptors in the skin, triggering anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive effects. This helps manage symptoms of eczema and psoriasis, such as irritation and swelling.
3. How should I apply Avate Ointment?
To apply Avate Ointment, start by cleansing the affected skin area with a mild, fragrance-free cleanser. Apply a thin layer of ointment to the area and gently massage it into the skin. Use once daily, as directed by your healthcare provider.
4. Are there any side effects of Avate Ointment?
Common side effects include localized symptoms like itching, burning, and erythema (redness). With prolonged use, there may be a risk of atrophic changes in the skin or pigmentation variations. If severe reactions occur, consult your healthcare provider.
5. Who should avoid using Avate Ointment?
Avate Ointment should not be used in individuals with viral skin diseases (such as herpes or varicella), tuberculosis, or a history of hypersensitivity to Methylprednisolone Aceponate. Always consult your healthcare provider before use to ensure it is appropriate for your condition.
