Clobederm-S Lotion 20ml (Clobetasol Propionate + Salicylic Acid)
Clobederm-S Lotion 20ml is a dual-action topical treatment combining Clobetasol Propionate (Class 1 / super-potent corticosteroid) with Salicylic Acid (keratolytic agent) for the management of scaly, hyperkeratotic, and inflammatory skin conditions. Clobetasol Propionate rapidly reduces inflammation and itch, while Salicylic Acid softens and removes thick scales — enhancing steroid penetration into the skin for superior efficacy on hyperkeratotic plaques. Indicated for scaly psoriasis, hyperkeratotic eczema, atopic dermatitis, neurodermatitis, and discoid lupus erythematosus. Prescription required. Maximum 2 weeks continuous use. Do NOT apply to face, groin, or armpits.
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Clobederm-s Lotion 20ml (clobetasol Propionate + Salicylic Acid)
Description
Clobederm-S Lotion: Your Solution for Skin Conditions
It is a specialized topical treatment that combines the potent action of Clobetasol Propionate and Salicylic Acid to
effectively address a range of skin conditions. In this article, we'll delve into the composition, indications, proper usage, and contraindications for Clobederm-S Lotion
Composition Clobederm-S Lotion
Clobederm-S Lotion brings together two active ingredients:
- Clobetasol Propionate USP: This compound possesses anti-inflammatory, antipruritic, and vasoconstrictive properties. It plays a crucial role in reducing skin inflammation and itching
- Salicylic Acid BP: Known for its keratolytic properties, Salicylic Acid is used topically to treat hyperkeratotic and scaly skin
conditions. It aids in the shedding of dead skin cells
Indications for Use
It is indicated for several skin conditions, including:
- Eczema: Effective for managing eczema and its related symptoms
- Atopic Dermatitis: Provides relief for those suffering from this common form of eczema
- Neurodermatitis: Addresses skin inflammation associated with neurodermatitis
- Psoriasis: Useful in controlling the symptoms of psoriasis
- Discoid Lupus Erythematosus: An essential treatment option for this autoimmune skin condition
Dosage and Administration
To use Clobederm-S Lotion effectively:
- Apply the lotion generously to completely cover the affected area
- Administer it twice daily, ideally in the morning and night
- It's essential not to exceed four weeks of continuous use without a medical review
Contraindications Clobederm-S Lotion
It is contraindicated in the following situations:
- Patients with hypersensitivity to any of its components
- Conditions like rosacea, acne vulgaris, perioral dermatitis, and primary cutaneous viral infections
Adverse Reactions
Common adverse reactions associated with the use of topical corticosteroids like include:
- Burning
- Stinging
- Irritation
- Pruritus (itching)
- Hypertrichosis
(excessive hair growth)
Important Instructions
- Keep the lotion out of children's reach
- Protect it from light and heat
- Store at temperatures below 30 °C
- Only use the lotion as directed by your physician
Presentation
- Clobederm-S Lotion is available in convenient 20ml plastic bottles, ensuring easy application and storage.
- Experience the relief and healing that can provide for various skin conditions. Consult with your healthcare provider for the best results and a personalized treatment plan
Usage & Benefits
- Dual-action combination: Clobetasol Propionate controls inflammation while Salicylic Acid removes scales and crusts
- Keratolytic action of Salicylic Acid breaks down thick psoriatic plaques and improves steroid absorption
- Superior to plain clobetasol for heavily scaled or hyperkeratotic lesions
- Rapidly relieves severe itch, redness, burning, and discomfort
- Lotion format suitable for scalp, body plaques, and larger skin surface areas
- Effective for psoriasis, atopic dermatitis, neurodermatitis, and discoid lupus erythematosus
- Manufactured by Atco Pharma — well-established, quality-certified Pakistani pharmaceutical manufacturer
How To Use
As directed by your dermatologist. This is a super-potent corticosteroid combination — strict adherence to prescribed dose and duration is essential.
General guidance: Apply generously to completely cover the affected area twice daily (morning and night). Do NOT apply to face, groin, or armpits. Do NOT use under occlusion unless specifically directed. Wash hands after application. Do NOT exceed 2 consecutive weeks of continuous use on any area. Do NOT exceed 50ml (equivalent to 50g) per week. Do not discontinue abruptly — taper under medical guidance.
FAQs
Is Clobederm-S Lotion a prescription product?
Yes. It contains Clobetasol Propionate 0.05%, a super-potent prescription-only corticosteroid. Use only under a dermatologist's supervision.
How is Clobederm-S different from plain Clobederm Lotion?
Clobederm-S adds Salicylic Acid to the base clobetasol formulation. Salicylic Acid is a keratolytic that softens and removes thick scales, making it particularly effective for heavily scaled psoriasis plaques or hyperkeratotic eczema where scale removal is needed before the steroid can penetrate adequately.
Why is the maximum use limited to 2 weeks?
Clobetasol Propionate is a Class 1 (super-potent) corticosteroid. Prolonged use causes skin thinning (atrophy), stretch marks, adrenal suppression, and systemic absorption effects. Two weeks is the standard maximum continuous course.
Can I use Clobederm-S on my face, scalp, groin, or armpits?
Do NOT apply to face, groin, or armpits — skin in these areas is thin and absorbs steroids at a much higher rate, increasing the risk of atrophy and systemic effects. Scalp psoriasis plaques (not the hairline or face) can be treated with lotion.
What is the maximum weekly dose?
Do not exceed 50ml per week. Exceeding this significantly increases the risk of HPA axis suppression.
Is this safe for children?
Clobetasol Propionate should not be used in children without specialist paediatric dermatology supervision due to higher systemic absorption risk.
What should I avoid using alongside Clobederm-S?
Avoid concurrent use with other corticosteroids or salicylic acid preparations on the same area. Do not use on infected skin without concurrent antimicrobial treatment.




