Coralan Tablets 7.5mg — Ivabradine for Heart Rate Control & Angina
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Description
About Coralan Tablets 7.5mg
Coralan Tablets 7.5mg contain Ivabradine 7.5mg — a selective inhibitor of the cardiac pacemaker If current in the sinoatrial node. By slowing spontaneous diastolic depolarisation, Ivabradine reduces heart rate precisely and safely, without lowering blood pressure, impairing cardiac contractility, or altering ventricular repolarisation. It is prescribed for patients with chronic stable angina who need controlled heart rate reduction to decrease chest pain frequency and improve exercise capacity.
Coralan 7.5mg is a prescription-only (Rx) medicine and must be used under cardiology supervision. It is contraindicated in resting heart rate below 60 bpm, severe hepatic impairment, and pacemaker-dependent patients. Avoid concurrent use with CYP3A4 inhibitors including grapefruit juice, diltiazem, and verapamil. The 7.5mg dose is typically prescribed when the 5mg dose has been well tolerated but requires dose titration for optimal heart rate control.
Key Benefits
- Higher-dose Ivabradine for optimised heart rate reduction in stable angina
- Selective sinus node inhibition — no blood pressure or contractility effects
- Reduces angina episodes and improves exercise tolerance
- Safe cardiac conduction profile — no AV or intraventricular conduction changes
- Well-suited for patients who require titration above 5mg dose
- Suitable alternative in beta-blocker-intolerant patients
How to Use
- Take Coralan 7.5mg exactly as prescribed by your cardiologist.
- Swallow tablet whole with water; do not crush or chew.
- Take twice daily with morning and evening meals for consistent blood levels.
- Avoid grapefruit juice and CYP3A4 inhibitors during therapy.
Frequently Asked Questions
Q: What is the difference between Coralan 5mg and 7.5mg?
A: The 7.5mg dose is a higher titration used when 5mg provides inadequate heart rate control. Your cardiologist will determine the appropriate dose based on your resting heart rate and clinical response.
Q: Does Coralan 7.5mg affect blood pressure?
A: No. Ivabradine acts exclusively on the sinus node If current — it does not lower blood pressure, making it safe for patients who cannot tolerate antihypertensive effects of beta-blockers.
Q: Can I stop Coralan suddenly?
A: Do not discontinue without consulting your cardiologist. Abrupt stoppage may worsen angina. Your doctor will guide you on dose tapering if needed.
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Usage & Benefits
- Higher-dose Ivabradine for optimised heart rate reduction in stable angina
- Selective sinus node inhibition — no blood pressure or contractility effects
- Reduces angina episodes and improves exercise tolerance
- Safe cardiac conduction profile — no AV or intraventricular conduction changes
- Well-suited for patients requiring titration above the 5mg dose
- Suitable alternative in beta-blocker-intolerant patients
How To Use
1. Take Coralan 7.5mg exactly as prescribed by your cardiologist.
2. Swallow tablet whole with water; do not crush or chew.
3. Take twice daily with morning and evening meals for consistent blood levels.
4. Avoid grapefruit juice and CYP3A4 inhibitors during therapy.
FAQs
What is the difference between Coralan 5mg and 7.5mg?
The 7.5mg dose is a higher titration used when 5mg provides inadequate heart rate control. Your cardiologist determines the appropriate dose based on your resting heart rate and clinical response.
Does Coralan 7.5mg affect blood pressure?
No. Ivabradine acts exclusively on the sinus node — it does not lower blood pressure.
Can I stop Coralan suddenly?
Do not discontinue without consulting your cardiologist. Abrupt stoppage may worsen angina; your doctor will guide dose tapering if needed.
