Cutis Tablets: Effective Treatment for Fungal Infections

Cutis Tablets Containing Terbinafine Hydrochloride

Composition:

Each tablet contains Terbinafine (as HCI) 250mg USP Specs

Indications:

Tinea capitis Onychomycosis (fungal nail infection) caused by dermatophyte fungi

Fungal skin infections, including tinea corporis, tinea cruris, tinea pedis, and yeast infections caused by Candida (e.g., Candida albicans) when oral therapy is considered appropriate due to the site, severity, or extent of the infection

Administration:

Adults: 250mg once daily

Children: No data available for children under 2 years of age. For children between 2 and 12 years, the dosage varies based on weight. Consult a healthcare provider for appropriate dosing

Duration of Treatment:

• Treatment duration varies based on the type and severity of the infection
• Complete resolution of symptoms may take several weeks after mycological cure
• For toenail onychomycosis, treatment typically lasts 612 weeks

Contraindications:

• Hypersensitivity to terbinafine or any of the excipients
• Chronic or active liver disease
• Patients with impaired renal function should receive half the normal dose

Special Warnings and Precautions:

• Elderly patients may require the same dosage as younger patients, but the possibility of preexisting
  liver or kidney impairment should be considered
• Terbinafine tablets should be discontinued if any symptoms of liver dysfunction occur, such as nausea, abdominal pain, or jaundice
• Patients with rare hereditary problems of galactose intolerance, severe lactose deficiency, or glucosegalactose malabsorption should not take Cutis tablets
• Use with caution in patients taking drugs metabolized by CYP2D6

Pharmacokinetic and Pharmacodynamic Properties:

• Terbinafine concentrates in the skin, hair, and nails
• It interferes with fungal sterol biosynthesis, leading to fungal cell death
• Terbinafine is fungicidal against dermatophytes
• Concentrations of terbinafine in the nail plate are associated with fungicidal activity

Undesirable Effects:

• Common side effects include musculoskeletal reactions (arthralgia, myalgia) and gastrointestinal symptoms
• Rare side effects may include hepatobiliary dysfunction, taste disturbances, neutropenia, agranulocytosis, and thrombocytopenia
• Very rare side effects include serious skin reactions, anaphylactoid reactions, and blood
  disorders

Presentation:

Cutis Tablets 125mg and 250mg are available in blister packs

It's essential to use Cutis Tablets under the guidance of a healthcare professional, especially when considering the dosage and potential side effects. If you experience any unusual symptoms while taking Cutis, consult your healthcare provider immediately

Usage and Benefits of Cutis Tablets

• Treats Various Fungal Infections: Effective against Tinea capitis, Onychomycosis, and other fungal skin infections.
• Promotes Fungal Cell Death: Terbinafine in Cutis Tablets inhibits fungal growth by disrupting fungal cell membrane synthesis.
• Improves Skin and Nail Health: Concentrates in skin, hair, and nails, ensuring targeted and effective treatment.
• Fungicidal Properties: Cutis Tablets are fungicidal against dermatophytes, providing long-lasting relief from fungal infections.
• Convenient Treatment: Oral medication ensures better absorption and results compared to topical treatments.

How to Use Cutis Tablets

Cutis Tablets are typically taken orally, with or without food. The standard adult dosage is 250mg once daily. For children aged 2-12 years, the dosage will vary depending on weight, and it’s essential to consult with a healthcare provider for proper dosing.

The duration of treatment varies based on the type and severity of the infection. For toenail onychomycosis, the treatment generally lasts 6-12 weeks. It’s important to complete the entire course as prescribed, even if symptoms improve before the treatment ends.

Do not alter the dosage or frequency without consulting your doctor.

1. What are Cutis Tablets used for?

Cutis Tablets, containing Terbinafine Hydrochloride, are used to treat fungal infections including Tinea capitis, Onychomycosis (nail fungal infections), and skin infections such as Tinea corporis, Tinea cruris, and Tinea pedis. They are also used for yeast infections like Candida albicans when oral therapy is necessary.

2. How should I take Cutis Tablets?

For adults, the recommended dosage is 250mg once daily. For children aged 2-12 years, the dosage will vary based on weight. Consult a healthcare provider for appropriate dosing. The duration of treatment depends on the infection type, typically lasting 6-12 weeks for toenail onychomycosis.

3. Are there any side effects of Cutis Tablets?

Common side effects include musculoskeletal pain (arthralgia, myalgia) and gastrointestinal symptoms. Rare side effects may include liver dysfunction, taste disturbances, and blood disorders. If you experience any unusual symptoms, seek medical advice immediately.

4. Can I take Cutis Tablets if I have liver or kidney issues?

Cutis Tablets should not be used in individuals with chronic or active liver disease. Patients with impaired renal function should receive half the normal dose. Always consult your healthcare provider before using Cutis Tablets if you have liver or kidney issues.

5. What precautions should I take while using Cutis Tablets?

Patients with a history of liver problems or certain genetic disorders (such as lactose intolerance) should avoid Cutis Tablets. Be cautious if you're taking medications metabolized by CYP2D6. If symptoms of liver dysfunction occur, such as nausea, abdominal pain, or jaundice, discontinue use and seek medical advice.