Daplozmet 5mg/850mg Tablet (Dapagliflozin + Metformin) for Type 2 Diabetes
- Combines dapagliflozin 5mg (SGLT2 inhibitor) with metformin 850mg (biguanide).
- Dual-action blood sugar control for adults with Type 2 diabetes.
- Cardiorenal benefit; low hypoglycaemia risk when used alone.
- Immediate-release tablet — take with food; prescription required.
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Daplozmet 5mg/850mg Tablet (dapagliflozin + Metformin) for Type 2 Diabetes
Description
Daplozmet 5mg/850mg Tablet – Dapagliflozin + Metformin Dual Therapy for Type 2 Diabetes
Daplozmet 5mg/850mg Tablet is a prescription oral antidiabetic medicine combining dapagliflozin 5mg (an SGLT2 inhibitor) with metformin 850mg (a biguanide). The two drugs act through complementary mechanisms — dapagliflozin removes excess glucose through the kidneys while metformin reduces hepatic glucose output and improves insulin sensitivity — producing stronger HbA1c reduction than either agent alone.
This immediate-release combination is commonly used in adults with Type 2 Diabetes when monotherapy no longer provides adequate control. It is weight-neutral to mildly weight-reducing, low risk for hypoglycaemia (unless paired with insulin or sulphonylurea), and offers cardiorenal benefit from the SGLT2 component.
Important cautions: hold Daplozmet during acute illness, dehydration, vomiting, or before planned surgery and contrast-imaging procedures (sick-day rules). Watch for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) and rare lactic acidosis from metformin. Not recommended if eGFR < 45 mL/min/1.73m². Take with food to reduce metformin-related stomach upset.
Use under medical supervision with diet, exercise, and periodic monitoring of blood sugar, kidney function and vitamin B12. See related options in our general medicines collection.
How to Order Daplozmet 5mg/850mg Tablet at Derma.pk
At Derma.pk, we ensure authenticity of Daplozmet 5mg/850mg Tablets, verified by licensed pharmacists. Delivery available across Pakistan. Prescription required. For inquiries contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
Usage & Benefits
- Dual mechanism: dapagliflozin removes glucose via urine; metformin lowers liver glucose output and improves insulin sensitivity.
- Stronger HbA1c reduction than either agent alone in adults with Type 2 diabetes.
- Cardiorenal protection from the SGLT2 component in suitable patients.
- Weight-neutral to mild weight loss in overweight Type 2 diabetes patients.
- Low hypoglycaemia risk unless combined with insulin or sulphonylurea.
How To Use
How to Use
- Take Daplozmet 5mg/850mg Tablet twice daily with meals, as prescribed.
- Swallow whole with water; do not crush or chew.
- Drink adequate fluids — dapagliflozin increases urination.
- Sick-day rule: hold during acute illness, vomiting, diarrhoea, dehydration, prolonged fasting, before contrast-imaging or planned surgery; resume only when eating and drinking normally.
- Stop and seek urgent care for symptoms of euglycaemic DKA (nausea, vomiting, abdominal pain, rapid breathing) or rare lactic acidosis (muscle cramps, weakness, breathing trouble).
- Not recommended if eGFR < 45 mL/min/1.73m².
- Monitor HbA1c, kidney function and vitamin B12 periodically.
FAQs
Frequently Asked Questions
Q: What is Daplozmet 5mg/850mg Tablet used for?A: It is a prescription combination of dapagliflozin and metformin used to improve blood sugar control in adults with Type 2 diabetes. Q: Why is it taken with food?A: Taking metformin with meals reduces nausea, diarrhoea and stomach upset, the most common side effects. Q: What is the eGFR cut-off?A: Metformin combinations are generally avoided when eGFR is below 45 mL/min/1.73m². Your doctor will review kidney function before prescribing. Q: What if I am sick or having surgery or a contrast scan?A: Hold the tablet during dehydration, vomiting, fasting, before contrast imaging or planned surgery, and resume when well. Q: What are the serious warning signs?A: Seek urgent care for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) or lactic acidosis (muscle cramps, weakness, breathing trouble). Q: How is this different from XR (extended-release)?A: This is immediate-release metformin, usually twice daily with meals. XR versions release slowly and are taken once daily, with better stomach tolerability. Q: Is a prescription required?A: Yes — Daplozmet is a prescription-only medicine.
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