Daplozmet XR 10mg/1000mg Tablet (Dapagliflozin + Metformin XR) for Type 2 Diabetes
- Combines dapagliflozin 10mg with high-strength extended-release metformin 1000mg.
- Highest-strength once-daily XR tablet in the Daplozmet range.
- Cardiorenal benefit at full SGLT2 dose; better stomach tolerability than IR metformin.
- Swallow whole — do not crush, split or chew; prescription required.
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Daplozmet Xr 10mg/1000mg Tablet (dapagliflozin + Metformin Xr) for Type 2 Diabetes
Description
Daplozmet XR 10mg/1000mg Tablet – Highest-Strength Once-Daily XR Therapy for Type 2 Diabetes
Daplozmet XR 10mg/1000mg Tablet is a prescription oral antidiabetic medicine combining dapagliflozin 10mg (an SGLT2 inhibitor) with extended-release metformin 1000mg. This is the highest-strength XR combination in the Daplozmet range, delivering full SGLT2 dosing alongside high-dose metformin in a single once-daily tablet with smooth extended release for improved stomach tolerability.
It is commonly prescribed for adults with Type 2 Diabetes Mellitus who need stronger glycaemic control or cardiorenal protection and who already tolerate higher metformin doses. Dapagliflozin removes excess glucose via the kidneys, while extended-release metformin reduces hepatic glucose output and improves insulin sensitivity throughout the day.
Important cautions: hold Daplozmet XR during acute illness, dehydration, vomiting, before contrast-imaging procedures, or planned surgery (sick-day rules). Watch for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) and rare lactic acidosis. Not recommended if eGFR < 45 mL/min/1.73m². Swallow XR tablets whole — do not crush, split or chew.
Use under medical supervision with diet, exercise, and periodic monitoring of blood sugar, kidney function and vitamin B12. See related options in our general medicines collection.
How to Order Daplozmet XR 10mg/1000mg Tablet at Derma.pk
At Derma.pk, we ensure authenticity of Daplozmet XR 10mg/1000mg Tablets, verified by licensed pharmacists. Delivery available across Pakistan. Prescription required. For inquiries contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
Usage & Benefits
- Highest-strength combination in the Daplozmet XR range for robust glycaemic control.
- Full SGLT2 dose: 10mg dapagliflozin for cardiorenal benefit.
- Extended-release metformin 1000mg: smooth all-day glucose lowering with better GI tolerability.
- Once-daily dosing: simple convenient regimen with the evening meal.
- Weight-neutral to mild weight loss in overweight Type 2 diabetes patients.
How To Use
How to Use
- Take one Daplozmet XR 10mg/1000mg Tablet once daily, usually with the evening meal.
- Swallow whole — do not crush, split or chew XR tablets.
- Drink adequate fluids — dapagliflozin increases urination.
- Sick-day rule: hold during acute illness, vomiting, dehydration, fasting, before contrast-imaging or planned surgery; resume only when eating and drinking normally.
- Stop and seek urgent care for symptoms of euglycaemic DKA or rare lactic acidosis.
- Not recommended if eGFR < 45 mL/min/1.73m².
- Monitor HbA1c, kidney function and vitamin B12 periodically.
FAQs
Frequently Asked Questions
Q: What is Daplozmet XR 10mg/1000mg Tablet used for?A: It is a prescription combination of full-dose dapagliflozin and high-strength extended-release metformin for adults with Type 2 diabetes. Q: How is this different from 10mg/500mg XR?A: This contains 1000mg of XR metformin instead of 500mg, used when stronger glycaemic control is needed and metformin is well-tolerated. Q: Can XR tablets be split or crushed?A: No. XR tablets must be swallowed whole — splitting damages the slow-release matrix. Q: What is the eGFR cut-off?A: Metformin combinations are generally avoided when eGFR is below 45 mL/min/1.73m². Q: What if I am sick or having surgery or a contrast scan?A: Hold the tablet during dehydration, vomiting, fasting, before contrast imaging or planned surgery, and resume when well. Q: What are the serious warning signs?A: Seek urgent care for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) or lactic acidosis (muscle cramps, weakness, breathing trouble). Q: Is a prescription required?A: Yes — Daplozmet XR is a prescription-only medicine.
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