Daplozmet XR 10mg/500mg Tablet (Dapagliflozin + Metformin XR) for Type 2 Diabetes
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Description
Daplozmet XR 10mg/500mg Tablet – Once-Daily Extended-Release Dual Therapy for Type 2 Diabetes
Daplozmet XR 10mg/500mg Tablet is a prescription oral antidiabetic medicine combining dapagliflozin 10mg (an SGLT2 inhibitor) with extended-release metformin 500mg. The XR formulation releases metformin slowly through the day, improving stomach tolerability and enabling convenient once-daily dosing, while dapagliflozin removes excess glucose via the kidneys.
This higher-strength dapagliflozin XR combination is commonly prescribed for adults with Type 2 Diabetes Mellitus who need the full 10mg SGLT2 dose for stronger glycaemic control or cardiorenal protection, alongside a lower metformin dose for tolerability. It is weight-neutral to mildly weight-reducing and low risk for hypoglycaemia when used alone.
Important cautions: hold Daplozmet XR during acute illness, dehydration, vomiting, before contrast-imaging procedures, or planned surgery (sick-day rules). Watch for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) and rare lactic acidosis. Not recommended if eGFR < 45 mL/min/1.73m². Swallow XR tablets whole — do not crush, split or chew.
Use under medical supervision with diet, exercise, and periodic monitoring of blood sugar, kidney function and vitamin B12. See related options in our general medicines collection.
How to Order Daplozmet XR 10mg/500mg Tablet at Derma.pk
At Derma.pk, we ensure authenticity of Daplozmet XR 10mg/500mg Tablets, verified by licensed pharmacists. Delivery available across Pakistan. Prescription required. For inquiries contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
- Full SGLT2 dose: 10mg dapagliflozin for stronger glucose lowering and cardiorenal benefit.
- Extended-release metformin: smooth release improves GI tolerability vs immediate-release.
- Once-daily dosing: simple convenient regimen, taken with the evening meal.
- Weight-neutral to mild weight loss in overweight Type 2 diabetes patients.
- Low hypoglycaemia risk unless paired with insulin or sulphonylurea.
How To Use
FAQs
What is Daplozmet XR 10mg/500mg Tablet used for?
It is a prescription combination of dapagliflozin 10mg and extended-release metformin 500mg for adults with Type 2 diabetes.
Why the 10mg dapagliflozin dose?
10mg is the full SGLT2 dose used when stronger glucose lowering or cardiorenal benefit is needed.
Can XR tablets be split or crushed?
No. XR tablets must be swallowed whole — splitting damages the slow-release matrix.
What is the eGFR cut-off?
Metformin combinations are generally avoided when eGFR is below 45 mL/min/1.73m².
What if I am sick or having surgery or a contrast scan?
Hold the tablet during dehydration, vomiting, fasting, before contrast imaging or planned surgery, and resume when well.
How is XR different from IR Daplozmet?
XR releases metformin slowly, allowing once-daily dosing with less GI upset; IR is taken twice daily with meals.
Is a prescription required?
Yes — Daplozmet XR is a prescription-only medicine.
