Daplozmet XR 5mg/500mg Tablet (Dapagliflozin + Metformin XR) for Type 2 Diabetes
- Combines dapagliflozin 5mg with extended-release metformin 500mg.
- Lower-strength once-daily XR starter combination for Type 2 diabetes.
- XR formulation improves stomach tolerability vs IR metformin.
- Swallow whole — do not crush, split or chew; prescription required.
Pay in 3 Installments of
Rs.
101
Daplozmet Xr 5mg/500mg Tablet (dapagliflozin + Metformin Xr) for Type 2 Diabetes
Description
Daplozmet XR 5mg/500mg Tablet – Once-Daily Starter XR Combination for Type 2 Diabetes
Daplozmet XR 5mg/500mg Tablet is a prescription oral antidiabetic medicine combining dapagliflozin 5mg (an SGLT2 inhibitor) with extended-release metformin 500mg. This lower-strength XR combination is a useful starting dose when initiating dual therapy or for patients who experience stomach side effects with immediate-release metformin.
Dapagliflozin removes excess glucose via the kidneys; extended-release metformin reduces liver glucose output and improves insulin sensitivity, releasing gradually for stable all-day blood sugar control with improved GI tolerability and once-daily dosing.
Important cautions: hold Daplozmet XR during acute illness, dehydration, vomiting, before contrast-imaging procedures, or planned surgery (sick-day rules). Watch for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) and rare lactic acidosis. Not recommended if eGFR < 45 mL/min/1.73m². Swallow XR tablets whole — do not crush, split or chew.
Use under medical supervision with diet, exercise, and periodic monitoring of blood sugar, kidney function and vitamin B12. See related options in our general medicines collection.
How to Order Daplozmet XR 5mg/500mg Tablet at Derma.pk
At Derma.pk, we ensure authenticity of Daplozmet XR 5mg/500mg Tablets, verified by licensed pharmacists. Delivery available across Pakistan. Prescription required. For inquiries contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
Usage & Benefits
- Gentle starter strength for new dual-therapy patients or those sensitive to metformin GI effects.
- Dual mechanism: dapagliflozin removes glucose via urine; metformin lowers liver glucose output.
- Extended-release metformin: smooth release improves stomach tolerability vs IR.
- Once-daily dosing: taken with the evening meal.
- Low hypoglycaemia risk unless paired with insulin or sulphonylurea.
How To Use
How to Use
- Take one Daplozmet XR 5mg/500mg Tablet once daily, usually with the evening meal.
- Swallow whole — do not crush, split or chew XR tablets.
- Drink adequate fluids — dapagliflozin increases urination.
- Sick-day rule: hold during acute illness, vomiting, dehydration, fasting, before contrast-imaging or planned surgery; resume only when eating and drinking normally.
- Stop and seek urgent care for symptoms of euglycaemic DKA or rare lactic acidosis.
- Not recommended if eGFR < 45 mL/min/1.73m².
- Monitor HbA1c, kidney function and vitamin B12 periodically.
FAQs
Frequently Asked Questions
Q: What is Daplozmet XR 5mg/500mg Tablet used for?A: It is a prescription starter combination of dapagliflozin and extended-release metformin for adults with Type 2 diabetes. Q: How is this different from 10mg/500mg XR?A: It contains 5mg of dapagliflozin instead of 10mg — a lower SGLT2 dose used at initiation or when full-dose dapagliflozin is not yet needed. Q: Can XR tablets be split or crushed?A: No. XR tablets must be swallowed whole — splitting damages the slow-release matrix. Q: What is the eGFR cut-off?A: Metformin combinations are generally avoided when eGFR is below 45 mL/min/1.73m². Q: What if I am sick or having surgery or a contrast scan?A: Hold the tablet during dehydration, vomiting, fasting, before contrast imaging or planned surgery, and resume when well. Q: What are the serious warning signs?A: Seek urgent care for euglycaemic DKA (nausea, vomiting, abdominal pain, fast breathing) or lactic acidosis. Q: Is a prescription required?A: Yes — Daplozmet XR is a prescription-only medicine.
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