Diajard-MXR 10mg/1000mg for Type 2 Diabetes
Diajard-MXR 10mg/1000mg Tablet combines empagliflozin 10mg (SGLT2 inhibitor) and metformin 1000mg extended release in a once-daily formulation for adults with type 2 diabetes. The XR formulation releases metformin gradually to improve tolerability and adherence. A prescription is required for this medication. Do not stop without consulting your doctor. Sick-day rule: temporarily stop during severe illness, dehydration, or when unable to eat — consult your doctor immediately. Risk of euglycaemic diabetic ketoacidosis (DKA): seek emergency care if you experience persistent nausea, vomiting, abdominal pain, or unusual fatigue. May increase risk of genital yeast infections and urinary tract infections. May cause dizziness — sit or stand up slowly. Take with food to reduce stomach upset.
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Diajard-mxr 10mg/1000mg for Type 2 Diabetes
Description
Diajard-MXR Tablets 10mg/1000mg – Extended-Release Dual Action Diabetes Therapy
Diajard-MXR Tablets 10mg/1000mg are a prescription oral antidiabetic medication used for the management of type 2 diabetes mellitus in adults. This dual-action formulation combines empagliflozin with metformin extended-release, providing effective and sustained blood sugar control with improved gastrointestinal tolerability.
Empagliflozin works by increasing the excretion of excess glucose through the kidneys, while metformin XR reduces glucose production in the liver and improves insulin sensitivity over an extended period. This complementary mechanism helps regulate both fasting and post-meal blood sugar levels while minimizing blood sugar fluctuations.
Diajard-MXR is particularly suitable for patients who require combination therapy with once-daily dosing convenience and long-acting metformin support. When taken regularly alongside a balanced diet and physical activity, it supports long-term diabetes management and helps reduce the risk of diabetes-related complications.
This medication should be used strictly under medical supervision, with regular monitoring of blood glucose levels to ensure safe and effective treatment.
How to Order Diajard-MXR 10mg/1000mg at Derma.pk
At Derma.pk, we ensure the authenticity of Diajard-MXR Tablets 10mg/1000mg, verified by licensed pharmacists. Delivery is available across Pakistan. For prescriptions or inquiries, contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
Once-daily extended-release metformin reduces gastrointestinal side effects vs immediate-release formulations
Empagliflozin 10mg provides proven SGLT2 inhibition and cardio-renal protective effects
Simplified once-daily dosing improves long-term adherence
Low intrinsic hypoglycaemia risk — neither agent forces insulin release
Extended-release matrix delivers smoother metformin blood levels throughout the day
Cardiovascular protection: empagliflozin reduces heart failure hospitalisation and CKD progression
How To Use
Take one Diajard-MXR 10mg/1000mg tablet once daily with the evening meal. Take with food to reduce stomach upset. Swallow whole — do not crush, cut, or chew, as this destroys the extended-release matrix. An inert tablet shell may appear in your stool — this is normal. Do not stop without consulting your doctor. Sick-day rule: temporarily stop during severe illness, vomiting, diarrhoea, dehydration, before contrast imaging, or before surgery — consult your doctor immediately. Risk of euglycaemic diabetic ketoacidosis (DKA): seek emergency care if you experience persistent nausea, vomiting, abdominal pain, or unusual fatigue — even when blood sugar seems normal. May increase risk of genital yeast infections and urinary tract infections. May cause dizziness — sit or stand up slowly. Avoid heavy alcohol. Monitor eGFR and B12 periodically.
FAQs
Why is extended release better than immediate-release metformin?
Metformin XR releases gradually, smoothing peak blood levels and significantly reducing nausea, diarrhoea, and stomach discomfort that are common with immediate-release formulations — especially at 1000mg doses.
Can I cut or crush this tablet?
No — you must swallow it whole. Crushing or chewing breaks the extended-release matrix and causes sudden, excessive metformin exposure, increasing side effect risk.
What are the sick-day rules for Diajard-MXR?
Temporarily stop during vomiting, diarrhoea, fever, dehydration, fasting, before contrast-dye imaging, or before surgery. Both DKA (from empagliflozin) and lactic acidosis (from metformin) risks increase — consult your doctor immediately.
What DKA symptoms require emergency care?
Seek emergency care immediately for persistent nausea, vomiting, abdominal pain, or unusual fatigue — even if blood sugar reads normal. This is euglycaemic DKA, a risk with SGLT2 inhibitors.
What is the minimum kidney function required?
This combination is contraindicated below eGFR 45 mL/min. Your doctor will monitor kidney function regularly during treatment.



