Diajard-MXR 5mg/1000mg for Type 2 Diabetes
Diajard-MXR 5mg/1000mg Tablet combines low-dose empagliflozin 5mg (SGLT2 inhibitor) with metformin 1000mg extended release in a once-daily fixed-dose tablet for adults with type 2 diabetes. The gentler SGLT2 dose is suitable when patients tolerate full metformin XR but need lower empagliflozin due to age, volume status, or kidney thresholds. A prescription is required for this medication. Do not stop without consulting your doctor. Sick-day rule: temporarily stop during severe illness, dehydration, or when unable to eat — consult your doctor immediately. Risk of euglycaemic diabetic ketoacidosis (DKA): seek emergency care if you experience persistent nausea, vomiting, abdominal pain, or unusual fatigue. May increase risk of genital yeast infections and urinary tract infections. May cause dizziness — sit or stand up slowly. Take with food to reduce stomach upset.
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Diajard-mxr 5mg/1000mg for Type 2 Diabetes
Description
Diajard-MXR Tablets 5mg/1000mg – Extended-Release Dual Action Diabetes Therapy
Diajard-MXR Tablets 5mg/1000mg are a prescription oral antidiabetic medication used for the management of type 2 diabetes mellitus in adults. This combination therapy contains empagliflozin and metformin extended-release, offering effective blood sugar control through complementary mechanisms with improved gastrointestinal tolerability.
Empagliflozin lowers blood glucose by increasing the excretion of excess glucose through the kidneys, while metformin XR works gradually to reduce glucose production in the liver and improve insulin sensitivity throughout the day. This dual mechanism helps manage both fasting and post-meal blood sugar levels while minimizing sudden glucose fluctuations.
Diajard-MXR 5mg/1000mg is particularly suitable for patients who require combination therapy with a lower empagliflozin dose while benefiting from high-dose extended-release metformin. When used consistently with a healthy diet and regular physical activity, it supports long-term diabetes control and reduces the risk of diabetes-related complications.
This medication should be taken strictly under medical supervision, with regular blood glucose monitoring to ensure treatment effectiveness and safety.
How to Order Diajard-MXR 5mg/1000mg at Derma.pk
At Derma.pk, we ensure the authenticity of Diajard-MXR Tablets 5mg/1000mg, verified by licensed pharmacists. Delivery is available across Pakistan. For prescriptions or inquiries, contact sales@derma.pk or WhatsApp +92-320-5999650.
Usage & Benefits
Low 5mg empagliflozin dose reduces volume-related effects while preserving cardio-renal benefit
Full 1000mg metformin XR supports insulin sensitivity with once-daily extended-release tolerability
Once-daily dosing simplifies adherence vs splitting immediate-release metformin doses
Low intrinsic hypoglycaemia risk — neither agent forces insulin release
Extended-release matrix reduces peak-related gastrointestinal side effects of metformin
Suitable for older patients or those with lower renal glucose thresholds
How To Use
Take one Diajard-MXR 5mg/1000mg tablet once daily with the evening meal. Take with food to reduce stomach upset. Swallow whole — do not crush, cut, or chew. An inert tablet shell may appear in your stool — this is normal for XR formulations. Do not stop without consulting your doctor. Sick-day rule: temporarily stop during severe illness, vomiting, diarrhoea, dehydration, before contrast imaging, or before surgery — consult your doctor immediately. Risk of euglycaemic diabetic ketoacidosis (DKA): seek emergency care if you experience persistent nausea, vomiting, abdominal pain, or unusual fatigue — even with normal blood sugar. May increase risk of genital yeast infections and urinary tract infections. May cause dizziness — sit or stand up slowly. Avoid heavy alcohol. Have eGFR and vitamin B12 monitored periodically.
FAQs
Why use 5mg empagliflozin with 1000mg metformin XR?
This combination suits patients who tolerate full 1000mg metformin XR but need the gentler 5mg empagliflozin dose — for example, older patients, those with lower renal glucose thresholds, or those managing volume-related dizziness.
Is the tablet shell in my stool harmful?
No. The inert XR matrix shell may pass visibly in your stool after the drug has been fully absorbed. This is completely normal and expected.
What are the sick-day rules?
Temporarily stop during vomiting, diarrhoea, fever, dehydration, fasting, before contrast-dye imaging, or before surgery. Both DKA (empagliflozin) and lactic acidosis (metformin) risks are elevated — consult your doctor immediately.
What DKA signs require emergency care?
Seek emergency care immediately for persistent nausea, vomiting, abdominal pain, or unusual fatigue — even when blood sugar appears normal. This is euglycaemic DKA, a known risk with SGLT2 inhibitors.
What is the minimum eGFR for this medication?
This combination is contraindicated below eGFR 45 mL/min. Your doctor will monitor kidney function regularly.
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