Epinum Cream (Lidocaine + Prilocaine) Effective Topical Anesthetic Cream

Description:

Epinum Cream is a topical anesthetic cream formulated with Lidocaine and Prilocaine. This eutectic mixture remains in liquid form due to its low melting point, offering efficient pain relief

Composition:

Each gram contains
Lidocaine USP 25 mg (2.5% w/w)

Prilocaine USP 25 mg
(2.5% w/w)

Pharmacodynamics:

• Lidocaine and Prilocaine provide dermal anesthesia by inhibiting pain receptors and nerve endings
• Maximal anesthesia is achieved after 12 hours of application, varying by skin location
• Effective for needle procedures, laser treatment, and curettage of molluscum contagiosum in pediatric patients
• Safe and efficacious for adult and elderly populations
• Application to the genital mucosa achieves rapid anesthesia (1520 minutes)
• Leg ulcers cleansing is achieved after 30 minutes of application
• No need for dose reduction in hepatic or renal impairment
• Infants under 37 weeks gestational age should not use it due to the risk of methemoglobinemia.

Warnings and Precautions:

• Avoid use in patients with hypersensitivity to lidocaine, prilocaine, or related compounds
• Exercise caution in patients with glucose6phosphate dehydrogenase deficiency and atopic dermatitis
• Prolonged application on atopic dermatitis may cause local vascular reactions
• Be cautious when applying near the eyes and rinse immediately if contact occurs
• Monitoring is necessary for patients on class I antiarrhythmics as their cardiac effects may accumulate.
• Lidocaine and prilocaine have bactericidal and antiviral properties at concentrations above
  0.52%

Use in Specific Populations:

• Effective in pediatric patients for various procedures
• Safe for the elderly population
• Hepatic or renal impairment does not require dosage adjustments.

Epinum Cream provides effective pain relief for a wide range of procedures and patient populations. It is a valuable addition to dermatological and medical practices for local anesthesia