Glucovance 250/1.25mg Tablets
Glucovance 250/1.25mg Tablets by Merck combine Metformin 250mg and Glibenclamide 1.25mg (also known as Glyburide) for dual-action Type 2 diabetes management. Controls blood glucose through complementary mechanisms. Prescription-only medicine at Derma.pk.
Pay in 3 Installments of
Rs.
55
Glucovance 250/1.25mg Tablets
Description
Glucovance 250/1.25mg Tablets — Glibenclamide & Metformin for Type 2 Diabetes
Glucovance 250/1.25mg Tablets by Merck combine two proven antidiabetic agents: Metformin 250mg (a biguanide) and Glibenclamide 1.25mg (a sulfonylurea). This dual-action combination provides complementary mechanisms to achieve superior glycaemic control in Type 2 diabetes mellitus. Note: Glibenclamide is also known internationally as Glyburide. A valid prescription is required.
Key Benefits
- Dual-action formula: Glibenclamide stimulates insulin secretion; Metformin reduces hepatic glucose output
- Complementary mechanisms achieve better HbA1c reduction than either agent alone
- Low-dose combination (1.25mg glibenclamide) reduces hypoglycaemia risk vs higher-dose sulfonylureas
- Metformin component improves peripheral insulin sensitivity and reduces hepatic gluconeogenesis
- Well-established Merck brand with proven clinical efficacy in Type 2 diabetes
How to Use
Take Glucovance 250/1.25mg Tablets once or twice daily with meals, or exactly as prescribed by your physician. Do not skip meals after dosing to avoid hypoglycaemia. Monitor blood glucose regularly.
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Usage & Benefits
- Dual-action antidiabetic: Glibenclamide boosts insulin secretion; Metformin reduces liver glucose output
- Superior HbA1c reduction compared to monotherapy in Type 2 diabetes
- Lower glibenclamide dose (1.25mg) reduces risk of hypoglycaemia
- Metformin reduces hepatic gluconeogenesis and improves insulin sensitivity
- Established Merck Glucovance brand with proven clinical track record
How To Use
Take Glucovance 250/1.25mg Tablets once or twice daily with meals, or as prescribed by your endocrinologist or physician. Always take with food to reduce gastrointestinal side effects and to prevent hypoglycaemia. Monitor blood glucose and HbA1c regularly. A valid prescription is required.
FAQs
What does Glucovance 250/1.25mg contain?
Glucovance 250/1.25mg contains Metformin 250mg (biguanide) and Glibenclamide 1.25mg (sulfonylurea, also known as Glyburide) — a dual-action combination for Type 2 diabetes.
Is Glucovance 250/1.25mg a prescription medicine?
Yes. Glucovance is a prescription-only antidiabetic combination. Send your prescription to sales@derma.pk or WhatsApp +92-320-5999650.
Why is the Glibenclamide dose only 1.25mg in this formulation?
The 1.25mg Glibenclamide dose is a lower starting strength, appropriate for patients new to combination therapy or those at higher risk of hypoglycaemia, while the Metformin provides complementary glucose control.



