Glucovance 500/2.5mg Tablet 30s (Metformin + Glibenclamide)
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Description
Glucovance 500/2.5mg Tablet contains Metformin 500mg and Glibenclamide 2.5mg — a fixed-dose combination of a biguanide and a sulfonylurea antidiabetic agent. It is indicated for the management of Type 2 diabetes mellitus. A valid prescription is required.
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Drug Information
- Active Ingredients: Metformin 500mg + Glibenclamide 2.5mg
- Drug Classes: Biguanide + Sulfonylurea (Antidiabetic Combination)
- Pack Size: 30 Tablets
- Manufacturer: Merck Serono
- Indication: Type 2 Diabetes Mellitus
- Rx Status: Prescription required
Mechanism of Action
Metformin reduces hepatic glucose output and improves peripheral insulin sensitivity (biguanide). Glibenclamide 2.5mg stimulates insulin secretion from pancreatic beta cells (sulfonylurea). Together they provide complementary dual-mechanism blood glucose control in Type 2 diabetes.
Important Safety Information
- Use only under the supervision of a qualified physician or diabetologist.
- Monitor blood glucose and renal function regularly as directed.
- Risk of hypoglycaemia — do not skip meals after taking this medication.
- Inform your doctor of all other medications before starting this combination.
Usage & Benefits
- Dual-Mechanism Control: Combines Metformin (reduces hepatic glucose production, improves insulin sensitivity) with Glibenclamide 2.5mg (stimulates insulin secretion) for complementary blood glucose control.
- Lower Glibenclamide Strength: The 2.5mg Glibenclamide dose is suitable for patients requiring a lower sulfonylurea component in combination therapy.
- Established Combination: Metformin + Glibenclamide is a widely used fixed-dose combination in Type 2 diabetes management guidelines.
- Convenient Pack: 30 tablets for monthly supply.
How To Use
1. Use as directed by your physician or diabetologist. Typically taken with meals to reduce gastrointestinal effects. Monitor blood glucose and renal function regularly. Do not alter the dose or discontinue without medical advice.
FAQs
What is Glucovance 500/2.5mg used for?
It is prescribed for the management of Type 2 diabetes mellitus using a dual-mechanism antidiabetic combination.
What are the active ingredients?
Metformin 500mg (biguanide) and Glibenclamide 2.5mg (sulfonylurea).
Is this available without a prescription?
No, antidiabetic medications require a valid prescription in Pakistan.
How does this differ from Glucovance 500/5mg?
This formulation contains Glibenclamide 2.5mg (lower strength). The 500/5mg formulation contains Glibenclamide 5mg (higher strength). Your doctor will prescribe the appropriate dose.
Who manufactures Glucovance 500/2.5mg?
It is manufactured by Merck Serono.
