Glusimet XR Tablets 50/500mg
Glusimet XR 50/500mg Tablets combine Sitagliptin 50mg (DPP-4 inhibitor) and Metformin XR 500mg (extended-release biguanide) for dual-action Type 2 diabetes management. The XR formulation ensures sustained glucose control with improved GI tolerability. Prescription-only at Derma.pk.
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Glusimet Xr Tablets 50/500mg
Description
Glusimet XR Tablets 50/500mg — Sitagliptin & Metformin XR for Type 2 Diabetes
Glusimet XR 50/500mg Tablets combine Sitagliptin 50mg (a DPP-4 inhibitor) with Metformin XR 500mg (an extended-release biguanide) for dual-mechanism glycaemic control in Type 2 diabetes mellitus. The extended-release (XR) Metformin formulation provides sustained action and improved gastrointestinal tolerability. A valid prescription is required.
Key Benefits
- Dual mechanism: Sitagliptin enhances incretin activity; Metformin XR reduces hepatic glucose output
- Extended-release Metformin provides sustained blood glucose control with fewer GI side effects
- DPP-4 inhibitor (Sitagliptin) stimulates insulin secretion in a glucose-dependent manner
- Reduces HbA1c effectively as a combination therapy for Type 2 diabetes
- Weight-neutral profile compared to sulfonylurea-based combinations
How to Use
Take one Glusimet XR 50/500mg Tablet once or twice daily with meals, or exactly as prescribed by your physician. Swallow whole — do not crush or chew the extended-release tablet. Monitor blood glucose and HbA1c regularly.
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Usage & Benefits
- DPP-4 inhibitor Sitagliptin boosts incretin hormones for glucose-dependent insulin secretion
- Metformin XR suppresses hepatic glucose production and improves insulin sensitivity
- Extended-release formulation reduces GI side effects vs immediate-release Metformin
- Effective HbA1c reduction through dual complementary mechanisms
- Weight-neutral therapy — less risk of weight gain versus sulfonylurea combinations
How To Use
Take one Glusimet XR 50/500mg Tablet once or twice daily with meals, as prescribed by your physician. Swallow the extended-release tablet whole — do not crush, break, or chew. Take with food to reduce GI discomfort. Monitor blood glucose and kidney function regularly. A valid prescription is required.
FAQs
What does Glusimet XR 50/500mg contain?
Glusimet XR 50/500mg contains Sitagliptin 50mg (a DPP-4 inhibitor) and Metformin XR 500mg (extended-release biguanide) — a dual-action combination for Type 2 diabetes.
Why is the Metformin in Glusimet XR extended-release (XR)?
The XR (extended-release) formulation releases Metformin slowly over time, providing sustained blood glucose control and significantly reducing the nausea and GI side effects common with standard Metformin.
Is Glusimet XR 50/500mg a prescription medicine?
Yes. Both Sitagliptin and Metformin in this combination are prescription-only. Send your prescription to sales@derma.pk or WhatsApp +92-320-5999650.




