Ivermec Tablets (Ivermectin) 3mg
Ivermec Tablets contain Ivermectin USP 3mg, a semi-synthetic broad-spectrum anthelmintic derived from avermectins. It selectively binds glutamate-gated chloride channels in parasites, causing paralysis and death. Indicated for intestinal strongyloidiasis and onchocerciasis, with dermatology use in scabies. Prescription required. Caution in pregnancy and not established as safe in children under 15 kg. Authentic Daneen Pharma supply with countrywide delivery.
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Ivermec Tablets (ivermectin) 3mg
Description
Ivermec Tablets USP 3mg: A Potent Anthelmintic Agent
Composition:
Each tablet of Ivermec USP 3mg contains 3mg of Ivermectin USP.
Description:
Ivermec (Ivermectin) is a semisynthetic anthelmintic agent administered orally. Derived from the avermectins, a class of potent broad-spectrum anti-parasitic agents isolated from Streptomyces avermitilis fermentation products.
Clinical Pharmacology:
Mechanism of Action: Ivermectin, a part of the avermectin class, selectively binds to gluta mate-gated chloride ion channels in invertebrate nerve and muscle cells. This binding increases cell membrane permeability to chloride ions, leading to parasite paralysis and death. It may interact with other ligand-gated chloride channels.
Pharmacodynamics:
Avermectins exhibit specificity due to the absence of glutamate-gated chloride channels in some mammals and their low affinity for mammalian ligand-gated chloride channels. Ivermectin has limited ability to cross the human blood-brain barrier and is effective against various nematodes, excluding adult Onchocerca volvulus.
Pharmacokinetics:
Upon oral intake, plasma Ivermectin concentrations correlate with dosage. Metabolism mainly occurs in the liver, with both Ivermectin and its metabolites primarily excreted in feces over about 12 days. Less than 1% is excreted in urine, with an approximate 18-hour plasma half-life.
Indications and Usage:
Ivermectin is indicated for treating:
- Strongyloidiasis of the intestinal tract
- Onchocerciasis
Contraindications:
Patients hypersensitive to any component of the product should not use Ivermectin.
Interactions:
Co-administration with warfarin may increase International Normalized Ratio (INR) based on post-marketing reports.
Use in Specific Populations:
- Pregnancy: Pregnancy Category C - avoid use.
- Nursing mothers should exercise caution as Ivermectin excretes in low concentrations in human milk.
- Pediatric Use: Safety in pediatric patients <15 kg not established.
- Geriatric Use: Caution in elderly due to potential decreased hepatic, renal, or cardiac function.
- Strongyloidiasis in Immunocompromised Hosts: Administer cautiously to immunocompromised patients.
Conclusion:
In conclusion, Ivermec (Ivermectin) Tablets USP 3mg effectively treats Strongyloidiasis and Onchocerciasis. However, its usage requires careful consideration due to specific populations, potential drug interactions, and contraindications for safe and effective use.
Usage & Benefits
- Single-dose oral therapy for many parasitic infections
- Effective against intestinal strongyloidiasis
- Standard treatment option for onchocerciasis (river blindness)
- Widely used by dermatologists for scabies under medical guidance
- Convenient 3mg tablet for weight-based dosing
- Generally well tolerated when used as prescribed
- Authentic Daneen Pharma product
How To Use
Take Ivermec on an empty stomach with water exactly as prescribed; dose is calculated by body weight (commonly 200 micrograms/kg). Scabies treatment is usually a single dose repeated at 7-14 days. Avoid use in pregnancy unless clearly necessary and use cautiously in breastfeeding. Not established for children under 15 kg. Inform your doctor if you take warfarin as INR may rise. Report unusual neurological symptoms promptly. Store below 30°C, away from light and moisture, out of reach of children. Prescription required.
FAQs
What is Ivermec used for?
Prescription Ivermectin for strongyloidiasis, onchocerciasis and dermatology indications such as scabies.
How is dosing calculated?
Doses are typically based on body weight (around 200 micrograms/kg), prescribed as 3mg tablets.
Can pregnant women take it?
Avoid in pregnancy unless clearly necessary; speak to your doctor about alternatives.
Do I take it with or without food?
It is best taken on an empty stomach with a full glass of water.
Does it interact with other medicines?
Inform your doctor of all medicines; an interaction with warfarin may raise INR.
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