Jardy Met 5/500mg Tablets are a fixed-dose combination of Valsartan 5mg, an angiotensin receptor blocker (ARB), and Metformin 500mg, a biguanide antidiabetic agent. This low-dose valsartan formulation is tailored for patients commencing combination therapy for co-existing Type 2 diabetes mellitus and hypertension, allowing careful dose titration of the ARB component while maintaining effective metformin therapy. Valsartan selectively blocks the AT1 receptor, reducing vasoconstriction and lowering blood pressure, while Metformin addresses hyperglycaemia through suppression of hepatic gluconeogenesis and improvement of cellular insulin uptake.

This starting-dose combination is appropriate for patients with mild hypertension or those being transitioned to combination ARB+biguanide therapy under medical supervision. As both conditions are chronic, long-term use with regular monitoring of blood pressure, fasting glucose, HbA1c, serum potassium, and renal function is essential. Metformin should be withheld temporarily before contrast procedures or any situation with elevated lactic acidosis risk (e.g., dehydration, sepsis, major surgery).

Common side effects include nausea, dizziness, gastrointestinal upset, and fatigue. Hyperkalaemia is a potential risk with ARB therapy. Lactic acidosis is a rare but serious risk with metformin in patients with renal insufficiency. A valid prescription is required. Do not alter the dose without consulting your healthcare provider, and take the tablet at the same time each day for consistent blood pressure and glucose control.

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