Nassa 15mg Tablets – Mirtazapine Antidepressant (NaSSA)
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Description
Nassa 15mg Tablets — Mirtazapine Antidepressant (Rx)
Nassa 15mg Tablets contain Mirtazapine, a NaSSA (Noradrenergic and Specific Serotonergic Antidepressant) — a class distinct from SSRIs. Mirtazapine works by blocking presynaptic α2-adrenergic receptors, increasing the release of both norepinephrine and serotonin indirectly. It also blocks 5-HT2 and 5-HT3 receptors, which reduces anxiety and improves sleep quality without the sexual side effects associated with SSRIs.
Nassa 15mg is prescribed for major depressive disorder (MDD), particularly when depression is accompanied by sleep disturbance, poor appetite, and significant anxiety. At 15mg, the antihistamine (H1 blocking) effect is prominent, making it especially sedating and helpful for patients who struggle with insomnia. It also stimulates appetite, beneficial for patients with depression-related weight loss.
Clinical profile: Unlike SSRIs, Mirtazapine does not cause sexual dysfunction. It acts quickly on sleep (often within the first week). Patients should be aware of significant weight gain and increased appetite. Do not stop abruptly — gradual tapering is required. Prescription-only medicine. Share your prescription at sales@derma.pk or WhatsApp 0320-5999650.
Key Benefits
- Treats major depressive disorder — NaSSA mechanism, not SSRI
- Strong sedative effect at 15mg — ideal when insomnia accompanies depression
- No sexual dysfunction (key advantage over SSRIs)
- Improves appetite and sleep quality from early in treatment
- Reduces anxiety via 5-HT2/5-HT3 receptor blockade
Prescription Required
Nassa 15mg is a prescription-only antidepressant. Never stop this medicine suddenly. Your doctor will guide gradual dose tapering. Send your prescription to sales@derma.pk or WhatsApp 0320-5999650.
Also available: antidepressants at Derma.pk. See all prescription medicines for more options.
Usage & Benefits
- Treats major depressive disorder — NaSSA mechanism, distinct from SSRIs
- Strong sedating effect at 15mg — beneficial when insomnia accompanies depression
- No sexual dysfunction (key clinical advantage over SSRIs)
- Improves appetite and reduces anxiety via 5-HT2/5-HT3 blockade
- Faster sleep benefit — often effective within the first week of treatment
How To Use
Take exactly as prescribed by your doctor — typically once daily at bedtime. Swallow whole with water. Do not stop without medical advice; gradual tapering is required to avoid discontinuation effects. Sedation is expected — avoid driving until stable on the dose. Do not combine with MAO inhibitors or alcohol.
FAQs
Is Mirtazapine (Nassa) an SSRI?
No. Mirtazapine is a NaSSA — it works by blocking α2-adrenergic receptors to increase norepinephrine and serotonin release, not by inhibiting serotonin reuptake. This gives it a different side-effect profile from SSRIs.
Why is the 15mg dose more sedating than 30mg?
At 15mg, Mirtazapine's antihistamine (H1) effect dominates over noradrenergic activity. At higher doses (30–45mg), increased noradrenergic stimulation partially counteracts the sedation.
Can I stop Nassa 15mg suddenly?
No. Abrupt discontinuation can cause withdrawal symptoms. Always taper gradually under your doctor's supervision.
Is a prescription required for Nassa 15mg?
Yes — prescription-only medicine. Send your valid Rx to sales@derma.pk or WhatsApp 0320-5999650.
