Natrilix SR 1.5mg Tablets – Indapamide Prolonged Release
Natrilix SR 1.5mg Tablets contain Indapamide in a sustained-release formulation — a non-thiazide sulfonamide diuretic for once-daily antihypertensive therapy. Unlike conventional thiazides, Indapamide acts primarily through vascular mechanisms and causes less metabolic disturbance. The SR formulation maintains stable plasma levels for 24-hour blood pressure control. Preferred in hypertensive patients with diabetes or metabolic concerns requiring a diuretic.
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Natrilix Sr 1.5mg Tablets – Indapamide Prolonged Release
Description
Natrilix SR 1.5mg Tablets – Indapamide Prolonged-Release Antihypertensive
Natrilix SR 1.5mg Tablets contain Indapamide in a sustained-release matrix, classified as a non-thiazide sulfonamide diuretic. Unlike conventional thiazide diuretics, Indapamide has a predominantly vascular action — it reduces peripheral vascular resistance through calcium channel modulation and mild natriuresis, resulting in effective blood pressure reduction with a favourable metabolic profile (lower risk of hypokalaemia, dyslipidaemia, or hyperuricaemia compared to older diuretics).
The prolonged-release formulation (SR) ensures stable plasma levels over 24 hours, making once-daily dosing effective and convenient. Natrilix SR is used in essential hypertension and is particularly suitable for patients in whom metabolic neutrality is a priority (e.g., patients with type 2 diabetes or renal impairment). Regular monitoring of serum electrolytes and blood pressure is recommended. Use only under physician supervision; patients with sulfonamide allergy should consult their doctor.
Key Benefits
- Sustained 24-hour blood pressure control with once-daily dosing
- Non-thiazide mechanism: better metabolic profile than classic thiazide diuretics
- Suitable for hypertensive patients with diabetes or metabolic concerns
- Long-established safety and efficacy data in essential hypertension
Related Products
View our anti-hypertensive collection or browse general medicines for related cardiovascular therapies.
How to Order at Derma.pk
Nationwide delivery across Pakistan. Email prescription to sales@derma.pk or WhatsApp +92-320-5999650. Prescription required.
Usage & Benefits
- Sustained-release formulation for 24-hour blood pressure control with once-daily dosing
- Non-thiazide mechanism: lower risk of hypokalaemia, dyslipidaemia, hyperuricaemia
- Preferred diuretic antihypertensive for patients with type 2 diabetes or metabolic syndrome
- Dual action: mild natriuresis + direct vascular relaxation
- Extensive clinical data supporting efficacy in essential hypertension
How To Use
Take one Natrilix SR 1.5mg tablet once daily, preferably in the morning, as prescribed by your doctor. Swallow whole — do not crush or chew. Monitor blood pressure and serum electrolytes periodically during long-term therapy. Patients with sulfonamide allergy should inform their doctor. Do not adjust dose without medical advice. Prescription required.
FAQs
What is Natrilix SR used for?
It is used to treat essential hypertension (high blood pressure) in adults using a long-acting diuretic mechanism.
What does SR mean?
SR stands for sustained-release — the formulation releases Indapamide gradually for consistent 24-hour blood pressure control.
Is Natrilix SR a thiazide diuretic?
No. Indapamide is a non-thiazide sulfonamide diuretic with a more favourable metabolic profile than classic thiazides like hydrochlorothiazide.
Can it be used in diabetic patients?
Yes, its metabolic neutrality makes it a preferred diuretic option in hypertensive patients who also have type 2 diabetes.
Is a prescription required?
Yes. Natrilix SR is a prescription antihypertensive medicine.



