Neogab 400mg Capsule
Neogab 400mg Capsule contains Gabapentin at a higher strength for moderate to severe neuropathic pain when lower doses are insufficient. Used for diabetic neuropathy, post-herpetic neuralgia, sciatica, and adjunct seizure control. Controlled substance — prescription required. Never stop abruptly. Significant dizziness and drowsiness expected.
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Neogab 400mg Capsule
Description
Neogab 400mg Capsule (Gabapentin)
Neogab 400mg Capsule contains Gabapentin, prescribed for moderate to severe neuropathic pain and as adjunct therapy in epilepsy. This higher-strength dose is indicated when lower doses (100mg or 300mg) have not provided sufficient pain control. Gabapentin modulates voltage-gated calcium channels, reducing hyperactive nerve signalling and providing sustained relief from chronic nerve pain.
Conditions Treated
- Severe diabetic peripheral neuropathy
- Post-herpetic neuralgia (shingles nerve pain)
- Sciatica and spinal injury nerve pain
- Partial seizures — adjunct therapy in epilepsy
- Central neuropathic pain and nerve compression syndromes
Important Precautions
- Controlled substance: Gabapentin carries risk of abuse, tolerance, and physical dependence — strictly follow the prescribed regimen
- Do not stop abruptly: Abrupt discontinuation can trigger seizures — dose must be gradually tapered under medical supervision
- Driving and alertness: Causes significant dizziness and somnolence — avoid driving or hazardous tasks until your response is known
- Respiratory depression: Serious risk when combined with opioids, sedatives, or alcohol — always disclose concurrent medications
- Renal function: Dose must be reduced in patients with impaired renal clearance
- Prescription required; higher dose requires specialist oversight
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Usage & Benefits
- Higher-strength dose for moderate to severe neuropathic pain
- Relieves severe burning, tingling, sharp shooting, and electric shock-like nerve pain
- Effective for diabetic neuropathy, post-herpetic neuralgia, and spinal injury pain
- Adjunct seizure therapy in partial epilepsy
- Reduces nerve pain-related sleep disruption
- For patients where 100mg or 300mg doses provided insufficient control
How To Use
Dosage (as directed by doctor): Typically 400mg one to three times daily as prescribed. Swallow whole with a full glass of water — do not crush or chew. Can be taken with or without food; taking at night may benefit from drowsiness effect. Do not stop suddenly — gradual taper mandatory to prevent seizure withdrawal. Avoid driving and machinery operation. Regular kidney function monitoring required.
FAQs
Why is 400mg prescribed instead of lower doses?
The 400mg dose is prescribed when 100mg or 300mg has not provided adequate neuropathic pain control or when the condition requires a higher therapeutic level.
Can I take Neogab 400mg at bedtime?
Yes — taking it at night is often recommended as drowsiness can be beneficial for sleep, and it provides overnight nerve pain relief.
What happens if I stop Gabapentin suddenly?
Abrupt discontinuation can provoke seizures even in non-epileptic patients. Always reduce the dose gradually under medical supervision.
Is 400mg safe long-term?
It can be used safely long-term under specialist supervision with periodic kidney function and tolerance monitoring.



