ONVATE CREAM (Fluticasone Propionate) Lotion/Cream: A Comprehensive Guide to Dermatological Relief

Introduction:

ONVATE CREAM, featuring Fluticasone Propionate, is a versatile solution available in both lotion and cream forms, designed to alleviate inflammatory and pruritic manifestations associated with atopic dermatitis. This comprehensive guide covers the composition, indications, dosage, contraindications, precautions, and more to ensure safe and effective use.

Composition:

• Onvate Lotion: Each milliliter contains 0.5 mg of Fluticasone Propionate BP.
• Onvate Cream: Each gram contains 0.5 mg of Fluticasone Propionate.

Indications:

Onvate Lotion/Cream specifically formulates to relieve inflammatory and pruritic manifestations of atopic dermatitis in patients 1 year of age or older. Note that the safety and efficacy of using Onvate for longer than 4 weeks in this population have not been established. Additionally, its safety and efficacy in pediatric patients below 1 year of age remain undetermined.

Dosage and Administration:

For conditions such as Rosacea and Atopic Dermatitis, apply a thin film of Onvate Lotion/Cream to the affected skin areas once daily, rubbing in gently.

Contraindications:

Onvate is contraindicated in the following cases:

• Acne vulgaris
• Perianal dermatitis
• Primary cutaneous viral infections (e.g., herpes simplex, chickenpox)
• Hypersensitivity to any of its ingredients
• Perianal and genital pruritus
• Dermatoses in infants under three months of age, including dermatitis and napkin eruptions

Precautions & Warnings:

Prolonged application of high doses to large areas of the body, especially in infants and children, may lead to adrenal suppression. Atrophic changes in the skin, such as thinning, striae, and dilatation of superficial blood vessels, may occur with prolonged use. Avoid contact with the eyes, and use appropriate antimicrobial therapy when treating inflamed lesions that have been infected. Topical corticosteroids should be withdrawn if there is a spread of infection.

Pregnancy and Lactation:

Consider administration during pregnancy only if the expected risk to the mother outweighs any potential risk to the fetus. No investigation has been conducted on the excretion into human breast milk.

Adverse Effects:

Possible adverse effects of Onvate Lotion/Cream include local burning and pruritus. Prolonged use may cause atrophic changes in the skin, hypertrichosis, and hypopigmentation. Hypercorticism may occur, especially in infants and children, and the use of corticosteroids has been reported to exacerbate signs and symptoms of dermatoses.

Drug Interaction:

There is no known drug interaction reported for Onvate.

Over-dosage:

Acute over-dosage is unlikely, but in the case of chronic overuse, features of hypercorticism may appear. Discontinue application in such cases.

Further Information:

• Onvate Lotion: 20ml in Plastic Bottle.
• Onvate Cream: Available in a Plastic Tube.

Instructions:

• Store between 15 °C-30 °C.
• Protect from light.
• Keep medicines out of the reach of children.
• Use only on medical advice.
• For external use only

Usage and Benefits of Onvate Lotion/Cream

• Relieves Inflammation: Reduces redness and swelling associated with atopic dermatitis and other inflammatory skin conditions.
• Alleviates Itching: Provides relief from pruritus (itching), making it an effective treatment for conditions like Rosacea.
• Gentle and Effective: Formulated with Fluticasone Propionate, Onvate is suitable for patients aged 1 year and above.
• Convenient Application: Easy to apply, with once-daily application recommended for continuous relief.
• Improves Skin Health: Aids in managing skin conditions with minimal side effects when used as directed.

How to Use Onvate Lotion/Cream

For the treatment of conditions like Rosacea and Atopic Dermatitis, apply a thin film of Onvate Lotion/Cream to the affected skin areas once daily. Gently rub it into the skin for better absorption. Make sure to follow your doctor’s prescribed dosage and avoid contact with your eyes or mucous membranes. If you experience any irritation or unusual reactions, consult your healthcare provider immediately.

Frequently Asked Questions

1. What is Onvate Lotion/Cream used for?

Onvate Lotion/Cream, containing Fluticasone Propionate, is used to relieve the inflammatory and pruritic manifestations of atopic dermatitis in patients aged 1 year or older. It helps alleviate itching, redness, and swelling associated with this condition.

2. How do I use Onvate Lotion/Cream?

For optimal results, apply a thin film of Onvate Lotion/Cream to the affected skin areas once daily. Gently rub it in and avoid contact with the eyes. It is important to follow your doctor’s instructions on dosage and duration.

3. Are there any contraindications for Onvate Lotion/Cream?

Yes, Onvate is contraindicated in patients with acne vulgaris, perianal dermatitis, primary cutaneous viral infections like herpes simplex and chickenpox, hypersensitivity to its ingredients, and dermatoses in infants under three months of age.

4. What precautions should I take when using Onvate Lotion/Cream?

Prolonged use, especially in infants and children, may cause adrenal suppression and skin thinning. Avoid using Onvate on broken or infected skin, and stop use if infection spreads. Additionally, avoid applying it near the eyes.

5. Can Onvate be used during pregnancy and breastfeeding?

Onvate should only be used during pregnancy if the benefits outweigh the risks. No studies have been conducted on the excretion of Fluticasone Propionate into breast milk, so use caution during breastfeeding and consult your doctor.