Prothiaden Tablets 25mg (Dothiepin) for Depression
- Prothiaden Tablets 25mg contain dothiepin (dosulepin), a tricyclic antidepressant by Abbott.
- Prescribed for depression, depression with anxiety and certain chronic neuropathic pain.
- Helps lift mood, improve sleep and reduce pain sensitivity over weeks of regular use.
- Prescription required — do not stop abruptly; taper under medical guidance.
- Authentic stock at Derma.pk, a licensed online pharmacy in Pakistan.
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Prothiaden Tablets 25mg (dothiepin) for Depression
Description
Prothiaden Tablets 25mg (Dothiepin) for Depression
Prothiaden Tablets 25mg contain dothiepin (dosulepin) hydrochloride, a tricyclic antidepressant by Abbott Laboratories. Doctors in Pakistan prescribe Prothiaden 25mg primarily for depression, including major depressive disorder where features of anxiety and disturbed sleep are also present. It is also used off-label for certain types of chronic neuropathic pain.
Dothiepin works by restoring the balance of brain neurotransmitters — mainly serotonin and noradrenaline — that influence mood, sleep, appetite and pain perception. Over a few weeks of regular use, it can lift low mood, ease anxiety associated with depression, improve sleep quality and reduce chronic pain sensitivity.
Prothiaden is a prescription medicine that needs careful follow-up. Therapeutic effects usually build up over 2–4 weeks. Do not stop Prothiaden abruptly — sudden withdrawal can cause symptoms such as headache, nausea, dizziness and sleep disturbance, so dose reduction must be gradual under medical guidance. Inform your doctor of any heart problems, glaucoma, urinary retention, epilepsy or other medicines you take, particularly other antidepressants and sedatives. Common side effects include dry mouth, drowsiness, blurred vision, constipation and weight changes.
Browse more options in our Tablets and Capsules range and explore wider General Medicines at Derma.pk — a licensed online pharmacy delivering authentic Abbott medicines across Pakistan.
How to Buy Prothiaden 25mg at Derma.pk
Add Prothiaden Tablets 25mg to your cart and share your valid prescription via email at sales@derma.pk or WhatsApp +92-320-5999650 for pharmacist verification.
Usage & Benefits
Usage and Benefits of Prothiaden 25mg
- Treats depression including major depressive disorder with anxiety features.
- Supports improved sleep quality and reduced night-time wakefulness.
- Can ease certain chronic neuropathic pain conditions when prescribed off-label.
- Low 25mg starting strength supports gradual dose titration.
- Authentic Abbott medicine available at Derma.pk with nationwide delivery.
How To Use
How to Use Prothiaden 25mg
Take Prothiaden 25mg exactly as prescribed by your doctor, usually once daily in the evening or at bedtime due to its sedating effect. Swallow the tablet whole with water. Allow 2 to 4 weeks for full antidepressant effect — continue treatment even if you do not feel improvement immediately. Do not stop Prothiaden abruptly; sudden withdrawal can cause headache, nausea and sleep disturbance, so any dose change must be gradual under medical supervision. Inform your doctor about heart problems, glaucoma, urinary retention, epilepsy and any other medicines, especially other antidepressants and sedatives.
FAQs
What is Prothiaden 25mg used for?
Prothiaden 25mg (dothiepin) is used to treat depression, including cases with anxiety and disturbed sleep, and certain chronic neuropathic pain conditions.
How long does Prothiaden take to work?
Antidepressant effects usually build up over 2 to 4 weeks of regular use. Continue treatment as prescribed even if results are not immediate.
Can I stop Prothiaden suddenly?
No. Stopping abruptly can cause withdrawal symptoms such as headache, nausea and sleep disturbance. Dose reduction must be gradual under medical guidance.
Does Prothiaden cause drowsiness?
Yes, drowsiness is common, which is why it is often taken in the evening. Avoid driving or operating machinery until you know how it affects you.
Do I need a prescription for Prothiaden 25mg in Pakistan?
Yes. Prothiaden 25mg is a prescription medicine. Share your prescription via sales@derma.pk or WhatsApp +92-320-5999650 to order from Derma.pk.



