What is Spiromide Tablets 20mg?

Spiromide Tablets 20mg are an essential combination of Furosemide and Spironolactone, primarily used to treat resistant oedema and manage conditions such as heart failure and liver cirrhosis. This medication works through its dual action – Furosemide is a powerful short-acting diuretic that helps reduce fluid retention, while Spironolactone serves as a potassium-sparing diuretic, preventing the loss of potassium in the body.

How Does Spiromide Work?

• Furosemide acts as a diuretic, promoting the excretion of water and salts through the urine. It works within an hour, and its effects usually last between four to six hours.

• Spironolactone, on the other hand, inhibits aldosterone, which helps maintain potassium levels while effectively promoting sodium excretion. The full benefits of Spironolactone take longer, typically up to two to three days.

Together, these medications help manage symptoms of heart failure, cirrhosis, and secondary hyperaldosteronism by reducing the build-up of fluid in the body, improving overall fluid balance and relieving oedema.

Indications for Use

• Resistant Oedema: Typically associated with heart failure and liver cirrhosis.

• Heart Failure: Helps in fluid management in chronic congestive heart failure.

• Liver Cirrhosis: Reduces the fluid retention that often accompanies liver cirrhosis.

• Secondary Hyperaldosteronism: Often caused by excessive aldosterone secretion.

Precautions and Side Effects

Precautions:

• Ensure you do not have a blockage in the urinary tract before starting the medication, as this could aggravate symptoms.

• Regular monitoring is necessary, especially for patients with hypotension or those at risk for electrolyte imbalances.

Common Side Effects:

• Dizziness, headache, nausea, and abdominal discomfort.

• Electrolyte imbalances, including low sodium or high potassium levels.

Serious Side Effects:

• Severe allergic reactions such as swelling of the face, lips, or tongue.

• Nephrotoxicity: Impairment of kidney function due to long-term use.

Drug Interactions

• ACE inhibitors, NSAIDs, potassium-sparing diuretics, and digoxin can interact with Spiromide Tablets.

• Be sure to inform your doctor about any medications you are currently taking to avoid harmful interactions.

Warnings

• Use with caution in patients with kidney or liver diseases.

• Hypotension: Can cause a drop in blood pressure, so it is essential to monitor regularly.

• Electrolyte Monitoring: Regular tests for sodium, potassium, and creatinine levels are required during therapy.

• Avoid use in pregnancy unless the potential benefits outweigh the risks.

Storage

• Store Spiromide Tablets 20mg at room temperature, away from direct light and heat. Ensure the product is kept out of the reach of children.
  

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