Triplixam 5/1.25/5mg Tablets – Triple-Combo Antihypertensive
Triplixam 5/1.25/5mg Tablets are a fixed-dose triple combination of Perindopril 5mg (ACE inhibitor), Indapamide 1.25mg (non-thiazide diuretic), and Amlodipine 5mg (calcium channel blocker). All three agents work through distinct mechanisms to deliver comprehensive blood pressure reduction. Indicated for adults already stabilised on the three individual components at these doses. Single daily tablet simplifies therapy and supports long-term adherence.
Pay in 3 Installments of
Rs.
437
Description
Triplixam 5/1.25/5mg Tablets – Triple-Action Antihypertensive
Triplixam 5mg/1.25mg/5mg is a fixed-dose triple combination of Perindopril 5mg (ACE inhibitor), Indapamide 1.25mg (non-thiazide diuretic), and Amlodipine 5mg (dihydropyridine calcium channel blocker). Each active ingredient targets a distinct antihypertensive pathway: Perindopril blocks the renin-angiotensin system to reduce vasoconstriction and aldosterone secretion; Indapamide reduces blood volume through mild natriuresis; and Amlodipine relaxes peripheral arterioles through calcium channel blockade. The combined effect delivers powerful, sustained blood pressure reduction with complementary renal and cardiovascular protection.
Triplixam is indicated for adults with essential hypertension who are already stabilised on the individual components at the same doses. Its fixed-dose single-tablet design reduces pill burden and promotes adherence. Routine monitoring of blood pressure, electrolytes, renal function, and potassium levels is essential during therapy. Perindopril is contraindicated in pregnancy and in patients with a history of ACE inhibitor-induced angioedema. Always use under specialist or physician supervision.
Key Benefits
- Three complementary mechanisms in one daily tablet for maximum BP reduction
- ACE inhibitor action provides additional renal protection in high-risk patients
- Reduces pill burden and improves long-term treatment adherence
- Addresses cardiovascular risk factors beyond blood pressure alone
Related Products
Explore our anti-hypertensive medicines or our full general medicines range for cardiovascular care.
How to Order at Derma.pk
Nationwide delivery across Pakistan. Email prescription to sales@derma.pk or WhatsApp +92-320-5999650. Prescription required.
Usage & Benefits
- Three complementary antihypertensive mechanisms in one daily tablet
- Perindopril (ACE inhibitor): inhibits RAAS, reduces vasoconstriction and aldosterone
- Indapamide 1.25mg: mild natriuresis with favourable metabolic profile
- Amlodipine 5mg: smooth long-acting peripheral vasodilation
- Additional renal and cardiovascular protection from ACE inhibitor component
- Reduces pill burden and improves adherence vs three separate tablets
How To Use
Take one Triplixam 5/1.25/5mg tablet once daily, preferably in the morning, as prescribed. Swallow whole with water. Monitor blood pressure, potassium, renal function, and electrolytes regularly. Do not use in pregnancy (ACE inhibitor contraindicated). Do not use in patients with a history of ACE inhibitor-induced angioedema. Do not adjust dose without specialist advice. Prescription required.
FAQs
What is Triplixam used for?
It treats essential hypertension in adults who require three antihypertensive agents: an ACE inhibitor, a diuretic, and a calcium channel blocker.
What are the three active ingredients?
Perindopril (ACE inhibitor), Indapamide (non-thiazide diuretic), and Amlodipine (calcium channel blocker).
Why combine three drugs in one tablet?
To reduce pill burden, improve adherence, and ensure consistent delivery of all three components at the correct doses.
Is Triplixam safe in pregnancy?
No. Perindopril (ACE inhibitor) is contraindicated in pregnancy and women of childbearing potential not using contraception.
Is a prescription required?
Yes. Triplixam is a prescription-only combination antihypertensive.
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