Viracure DS 500mg Tablets (Famciclovir) - Pack of 21
Viracure DS 500mg Tablets contain famciclovir, an oral prodrug of penciclovir that inhibits viral DNA polymerase. Prescription required. Indicated for herpes zoster (shingles), recurrent or initial genital herpes (HSV-2), recurrent orolabial herpes (cold sores) and chronic suppressive therapy in immunocompetent and HIV-infected adults under specialist guidance. Rapidly absorbed - peak penciclovir levels are reached within about 45 minutes. Most courses are short (1-10 days) depending on the indication. Safety: dose adjustment is needed in renal impairment. Common side effects include headache and nausea. Manufactured by Atco, supplied as a pack of 21 tablets via derma.pk.
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Viracure Ds 500mg Tablets (famciclovir) - Pack of 21
Description
VIRACURE DS TABLETS (FAMCICLOVIR TABLETS USP) 500mg PACK OF 21 TABLETS: A Comprehensive Guide
Description:
Viracure tablets contain Famciclovir as the active
ingredient, a prodrug of the antiviral agent penciclovir. Famciclovir is
chemically known as 222amino9Hpurin9yl) ethyl1,3propanediol diacetate, with a
molecular formula C14H19NsO4 and a molecular weight of 321.3
Pharmacological Properties:
Mechanism of Action: Famciclovir is converted into
penciclovir in the body, which has antiviral activity against herpes simplex
virus 1 and 2, varicellazoster virus, EpsteinBarr virus, and cytomegalovirus.
Penciclovir inhibits viral DNA chain elongation by competitive inhibition with
deoxyguanosine triphosphate, halting virus replication
Pharmacokinetics:
- Absorption:
Famciclovir is rapidly and extensively absorbed, with bioavailability greater
than 90%. Peak plasma concentration of penciclovir occurs within 45 minutes
postdose - Distribution:
Penciclovir and its precursor are poorly bound to plasma proteins - Metabolism and
Elimination: Famciclovir is primarily eliminated as penciclovir in urine, with
no unchanged Famciclovir detected. The halflife of penciclovir is approximately
2 hours
Indications:
Herpes Labialis (Cold
Sores): Treatment of recurrent herpes labialis
Genital Herpes:
- Recurrent episodes: Treatment of recurrent
genital herpes - Suppressive therapy: Chronic suppressive
therapy of recurrent genital herpes
HIV Infected Adult Patients:
- Herpes Zoster
(Shingles): Treatment of herpes zoster - Limitation of Use: Viracure's efficacy and safety have not
been established for patients <18 years of age and for first episodes of
genital herpes in HIVinfected adults - Adverse Effects: Common adverse events include headache and
nausea, usually mild or moderate in nature - Special Populations:
- Pregnancy: Category
B; use during pregnancy should consider potential benefits vs. risks - Nursing Mothers: Use
with caution; excretion in human milk is unknown - Pediatric Population:
Safety and efficacy not established in children <18 years - Elderly Patients:
Dose modification not required unless renal function is impaired - Fertility: No impact
on male fertility observed in longterm treatment - Renal Impairment on
Hemodialysis: Administer Famciclovir immediately after hemodialysis - Hepatic Impairment:
No dose adjustment required in mild or moderate hepatic impairment - Warnings and Precautions:
Viracure contains
lactose
- Acute renal failure
risk; dosage reduction in renal impairment - Hypersensitivity
reactions - Avoid sexual
intercourse during outbreaks and practice safer sex during suppressive therapy
Contraindications:
Hypersensitivity to
the active substance or excipients
Drug Interactions:
Probenecid may
increase plasma concentrations of penciclovir; monitor for toxicity
Raloxifene may
inhibit the conversion of Famciclovir to penciclovir; monitor antiviral therapy
efficacy
This comprehensive guide provides detailed information about
Viracure DS tablets, their pharmacological properties, indications, special
populations, adverse effects, and more. Always consult a healthcare
professional for personalized guidance on medication use
Usage & Benefits
Key Benefits
- Effective oral antiviral for herpes zoster (shingles), genital herpes and recurrent cold sores
- Faster pain resolution and shorter outbreak duration when started early in herpes zoster
- Rapid absorption and conversion to active penciclovir, with sustained intracellular antiviral effect
- Short, simple regimens - many indications use 1-10 day courses
- Useful for suppressive therapy in patients with frequent recurrences under medical supervision
- 21-tablet pack covers typical herpes zoster or genital herpes treatment courses
How To Use
How to Use
1. Use only as prescribed - your doctor will choose the dose based on indication and renal function.
2. Herpes zoster (shingles): typically 500mg three times daily for 7 days, started within 72 hours of rash onset.
3. Recurrent genital herpes: a short course such as 1000mg twice daily for 1 day, started at the earliest sign of recurrence.
4. Recurrent orolabial herpes (cold sores): often a single 1500mg dose taken at first symptoms.
5. Swallow tablets whole with water, with or without food, at evenly spaced intervals.
Dose reduction is required in moderate to severe renal impairment - your doctor will calculate this. Drink plenty of fluids during treatment. Tell your doctor if you have a history of kidney disease. Store below 30 degrees Celsius and out of reach of children.
FAQs
Is Viracure DS a prescription medicine?
Yes - famciclovir is a prescription antiviral. Your doctor will confirm the diagnosis and choose the right dose for your kidney function.
When should I start treatment for shingles?
Famciclovir works best when started within 72 hours of shingles rash appearing. Early treatment reduces pain and shortens the outbreak.
How is famciclovir different from acyclovir?
Famciclovir is the prodrug of penciclovir, which has a long intracellular half-life, allowing less frequent dosing than acyclovir for some indications.
What are common side effects?
Headache and nausea are most common; dizziness, fatigue and rash can also occur. Severe side effects are uncommon at standard doses.
Can I take it in pregnancy or breastfeeding?
Safety data are limited - use only if your doctor judges the benefit outweighs the risk. Discuss with your doctor before starting.
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