Ziapine XR Quetiapine 300mg Tablet
- Ziapine XR 300mg — prescription extended-release second-generation antipsychotic
- Contains Quetiapine Fumarate XR — once-daily 24-hour symptom control
- Higher-dose XR formulation for schizophrenia and bipolar disorder
- Different from Ziapine 25mg and 100mg IR tablets — do not substitute without physician guidance
- Prescription Required — metabolic and QTc monitoring required
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Ziapine Xr Quetiapine 300mg Tablet
Description
Ziapine XR 300mg Tablet — Quetiapine Extended-Release Antipsychotic
Ziapine XR 300mg Tablet contains Quetiapine Fumarate in an extended-release (XR) formulation, designed for once-daily dosing. It is a second-generation (atypical) antipsychotic (SGA) prescribed for schizophrenia, bipolar disorder (manic and depressive episodes), and as adjunct therapy in major depressive disorder (MDD).
At 300mg XR, Ziapine XR delivers a sustained therapeutic plasma level throughout the 24-hour dosing interval, reducing peak-trough fluctuations compared to immediate-release tablets. This higher dose is typically used in schizophrenia and acute bipolar mania. The XR formulation is distinct from Ziapine 25mg and 100mg immediate-release tablets — do not substitute without physician guidance, as bioavailability profiles differ.
Metabolic monitoring is essential: monitor weight, fasting glucose, HbA1c, and lipid profile at baseline and periodically. QTc prolongation risk should be assessed, especially with concomitant medications.
Prescription Required. Available at Derma.pk with valid prescription. This is a different formulation and dose from Ziapine 25mg and 100mg — selection is strictly under psychiatrist or physician supervision.
How to Buy Ziapine XR 300mg Tablets from Derma.pk
- Visit Derma.pk and search for Ziapine XR Quetiapine 300mg Tablet.
- Upload your valid prescription via email sales@derma.pk or WhatsApp +92-320-5999650.
- Get safe and fast delivery anywhere in Pakistan.
Usage & Benefits
- Once-daily XR dosing for 24-hour control of schizophrenia symptoms
- Stabilises bipolar disorder — both manic and depressive phases
- Reduces hallucinations, delusions and disorganised thoughts
- Steady plasma levels with fewer peak-trough fluctuations versus IR tablets
- Adjunct therapy for major depressive disorder at appropriate doses
How To Use
1. Use as directed by your physician or psychiatrist.
2. Take once daily, preferably in the evening — do not crush, split or chew (must be swallowed whole).
3. Can be taken with a light meal or without food.
4. Do not substitute for Ziapine 25mg or 100mg IR without physician guidance — bioavailability profiles differ.
5. Monitor weight, fasting glucose, lipid profile and QTc at baseline and periodically; do not stop abruptly.
FAQs
How is Ziapine XR 300mg different from Ziapine 100mg tablets?
Ziapine XR is an extended-release formulation at a higher dose (300mg), providing once-daily dosing with more stable plasma levels. Ziapine 100mg is immediate-release. The two are not interchangeable without physician guidance.
Why is metabolic monitoring important at 300mg?
Higher-dose quetiapine has a greater risk of weight gain, glucose dysregulation and dyslipidaemia. Baseline and periodic monitoring of weight, fasting glucose, HbA1c and lipids is essential.
Can I cut or crush the XR tablet?
No — the extended-release mechanism is destroyed if the tablet is crushed or split. Swallow whole to ensure proper, sustained drug release.
What is the risk of QTc prolongation?
Quetiapine at higher doses has greater QTc-prolonging potential. ECG monitoring is recommended, especially when combined with other QTc-prolonging medicines.
Do I need a prescription?
Yes — Ziapine XR 300mg is a prescription-only medicine available at Derma.pk with a valid prescription.
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