Last updated: 16 June 2026 · Reviewed by Dr. Eram Razzaq, Consultant Dermatologist (PMDC 50606-B), June 2026.

Ketoconazole shampoo is the dermatologist's first choice when ordinary anti-dandruff products stop working. In Pakistan's hot, humid climate — where sweat and oil feed the scalp yeast behind most dandruff — a medicated 2% ketoconazole shampoo can calm flaking, itching and redness within a few washes. In this guide, you'll learn how ketoconazole works, which brands are available at Derma.pk, their latest 2026 prices, how to use them safely, and when it's time to see a dermatologist.

What Is Ketoconazole Shampoo?

Ketoconazole shampoo is an antifungal cleanser, usually formulated at 2% strength, that targets Malassezia — the yeast that lives on everyone's scalp but overgrows in oily, humid conditions. By disrupting the fungal cell membrane, ketoconazole reduces yeast numbers, which in turn settles the flaking, itching and inflammation of dandruff and seborrheic dermatitis. A landmark double-blind, placebo-controlled trial found 2% ketoconazole shampoo both cleared scalp seborrheic dermatitis and helped prevent relapse when used once weekly (NCBI/PubMed).

Why Choose a Medicated Ketoconazole Shampoo?

• Broad antifungal action: Unlike cosmetic anti-dandruff shampoos that only slow flaking, ketoconazole tackles the yeast that commonly drives the problem.
• Anti-inflammatory effect: It helps reduce the redness and irritation that come with seborrheic dermatitis.
• Long gaps between washes: Once your scalp is under control, many people maintain results with just one wash a week.
• Works beyond the scalp: Ketoconazole is also commonly used for tinea versicolor (fungal discolouration on the chest and back).

Best Ketoconazole Shampoos in Pakistan (2026 Prices)

Here are the ketoconazole shampoos and lotions currently stocked at Derma.pk, with their latest verified prices. Prices can change — tap any product to see the live price and pack size.

For everyday dandruff and seborrheic dermatitis, the 60ml 2% options — Conaz, Genketo and Hyseke — are the most popular and budget-friendly. Keto-Z is a larger hair-and-body format some people prefer when fungal issues extend beyond the scalp.

Which Ketoconazole Shampoo Should You Choose?

All of these contain the same 2% active, so the differences come down to budget, format and how widespread your symptoms are:

• On a tight budget: Genketo and Conaz give you proven 2% ketoconazole at the lowest price points.
• Persistent or severe dandruff: Hyseke and Ketonaz are popular picks many dermatologists reach for when flaking keeps returning.
• Fungal issues on the body too: the larger Keto-Z hair-and-body format is convenient for the chest, back and scalp together.
• Sensitive scalp: start with a single weekly wash, patch test, and build up only if tolerated.

Whichever you pick, consistency matters more than the brand — using any 2% ketoconazole shampoo correctly for a few weeks beats switching products every few days.

How to Use Ketoconazole Shampoo Safely

1. Wet your hair and scalp thoroughly.
2. Apply a generous amount and massage gently into the scalp — not just the hair.
3. Leave it on for 3–5 minutes so the active ingredient can work, then rinse well.
4. During a flare, use it about twice a week; once the scalp is calm, many people maintain with once a week.
5. Always follow the directions on your product's packaging, or your dermatologist's advice.

For a detailed, step-by-step routine, read our companion guide on how to use Conaz Shampoo safely. If you're comparing wider options, see our roundup of the best medicated shampoos for dandruff in Pakistan.

Possible Side Effects

Ketoconazole shampoo is generally well tolerated. Some people notice temporary dryness, a change in hair texture, mild itching or, rarely, irritation where it's applied. If you develop a rash, significant burning or hair shedding that concerns you, stop use and speak to a dermatologist. Do a patch test first if you have a sensitive or reactive scalp.

Is Ketoconazole Shampoo Safe in Pregnancy?

Only a small amount of ketoconazole is absorbed through the scalp, and topical use is often considered low-risk — but pregnancy and breastfeeding are individual situations. Please consult your doctor before use during pregnancy or while breastfeeding.

When to See a Dermatologist

Ketoconazole shampoo manages dandruff and seborrheic dermatitis, but it isn't a cure-all. Book a dermatologist visit if:

• Your flaking, itching or redness doesn't improve after 4 weeks of correct use.
• You have painful, weeping, crusted or bleeding patches on the scalp.
• You're losing hair in patches, or the scalp problem is spreading to the face or body.
• You're pregnant, breastfeeding, or treating a child, and want tailored advice.

The American Academy of Dermatology notes that persistent dandruff can be a sign of an underlying condition such as psoriasis or a fungal infection that needs prescription treatment (AAD: How to treat dandruff).

Frequently Asked Questions

Is ketoconazole shampoo safe for daily use?

It's designed for intermittent use — usually 2–3 times a week during a flare and once weekly for maintenance. Daily use isn't normally needed and can be drying, so follow the pack directions or your dermatologist's advice.

How long until I see results?

Many people notice less itching and flaking within 2–4 weeks of regular use. Studies show meaningful improvement in dandruff severity by week 4.

Can I use conditioner after ketoconazole shampoo?

Yes. Rinse the medicated shampoo out fully first, then apply conditioner to the mid-lengths and ends to keep hair soft.

What are the common side effects?

Temporary dryness, changes in hair texture and mild scalp itching are the most common. Serious irritation is uncommon — stop use and see a doctor if it occurs.

Is it safe during pregnancy?

Topical absorption is low, but you should consult your doctor before use during pregnancy or breastfeeding.

Can men and women both use ketoconazole 2%?

Yes. A 2% ketoconazole shampoo is suitable for both men and women dealing with dandruff or seborrheic dermatitis.

Does it help with hair fall?

By calming scalp inflammation, ketoconazole may support a healthier scalp environment. It is not a licensed hair-loss treatment, so see a dermatologist if hair fall is your main concern.

Can I use it on coloured hair?

Generally yes, but medicated shampoos can affect some colour treatments. Space out washes and follow your colourist's guidance if you've recently coloured your hair.

The Bottom Line

A 2% ketoconazole shampoo is a clinically supported, affordable way to manage dandruff and seborrheic dermatitis in Pakistan's climate. Start with a 60ml option such as Conaz, Genketo or Hyseke, use it correctly, and protect your scalp long-term. Shop authentic, dermatologist-recommended ketoconazole shampoos at Derma.pk — and if symptoms persist, see a dermatologist.

Reviewed by Dr. Eram Razzaq, Consultant Dermatologist (PMDC 50606-B), June 2026. This article is for general information and does not replace personalised medical advice.