Arynoin (Isotretinoin) Capsule 20mg — Pack of 30
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Description
Arynoin Capsule (ISOTRETINOIN) 20mg PACK OF 30 SOFT GELATIN CAPSULES: Unlocking Clearer Skin with Isotretinoin Soft Gelatin Capsules
Composition:
Each contains: Isotretinoin BP (Mfg. Specs, BP) 40mg Clinical Particulars
Therapeutic Indications:
A treats severe forms of acne (nodular or conglobate acne, or acne prone to permanent scarring) and acne that hasn't responded to standard therapies involving systemic antibacterial and topical therapy.
Dosage and Method of Administration:
Physicians experienced in systemic retinoid use and knowledgeable about its teratogenic risks should exclusively prescribe Arynoin. Therapy should begin at 0.5 mg/kg daily, with most patients requiring 0.51.0 mg/kg daily. Severe cases may require up to 2.0 mg/kg daily. Take capsules with food once or twice daily. A cumulative dose of 120150 mg/kg per treatment is common, with a duration of 1624 weeks. Remission often occurs after one course. In case of relapse, another course may be given with the same dose
Special Dosage Instructions
Patients with Renal Impairment:
Start at a lower dose (e.g., 10 mg/day) and increase up to 1 mg/kg/day or the maximum tolerated dose
Contraindications:
- Women in childbearing potential
- Pregnant or breastfeeding women
- Patients receiving tetracyclines
- Hepatic insufficiency
- Preexisting hypervitaminosis A
- Elevated blood lipid values
- Hypersensitivity to isotretinoin
Arynoin Is Teratogenic:
Pregnancy must be avoided. Female patients must:
- Use effective contraception for 1 month before, during, and after treatment
- Have a negative pregnancy test
- Start therapy on the 2nd or 3rd day of their menstrual period
- Understand the risk and need for rigorous follow-up
Psychiatric Disorders:
- Reports have indicated depression, psychosis, and rare suicide attempts.
Skin and Subcutaneous Tissue Disorders:
Initial acne exacerbation may occur but usually subsides within 710 days. Sun exposure should be avoided
Eye Disorders:
Dry eyes, corneal issues, decreased night vision, and others may occur but often resolve after treatment discontinuation
Musculoskeletal and Connective Tissue Disorders:
Myalgia, arthralgia, and increased serum creatine phosphokinase can occur
Benign Intracranial Hypertension:
Rare cases have been reported
Hepatobiliary Disorders:
Monitor liver function or enzymes and note transient increases.
Renal Insufficiency:
Arynoin can be given to patients with renal insufficiency
Lipid Metabolism:
Monitoring serum lipids is necessary, and elevated triglyceride levels (>800 mg/mL) can associate with acute pancreatitis.
This comprehensive description provides important information about Arynoin (Isotretinoin), its indications, dosing, contraindications, teratogenic risks, and potential side effects, enabling informed medical decisions
Usage & Benefits
- Indicated for severe nodular and conglobate acne under qualified dermatologist supervision only
- Addresses acne unresponsive to systemic antibiotics and topical therapies — as prescribed by a specialist
- Contains Isotretinoin BP 20mg per soft gelatin capsule (3 × 10 blister pack)
- Suppresses sebaceous gland activity and exhibits anti-inflammatory action under medical direction
- Manufactured by Pharma-health, verified and dispensed through derma.pk with prescription
- Explore the complete isotretinoin range at derma.pk
- Browse all anti-acne prescription products available at derma.pk
- Note: All described benefits apply strictly under dermatologist supervision. This is not an OTC product.
How To Use
Take exactly as prescribed by your dermatologist. Do not self-medicate.
1. Take capsules with food, once or twice daily at the dose prescribed by your dermatologist.
2. Starting dose is typically 0.5 mg/kg/day — your dermatologist will adjust based on response.
3. Complete the full course (typically 16–24 weeks with cumulative dose 120–150 mg/kg) as prescribed.
4. Women of childbearing potential must use two effective forms of contraception for 1 month before, during, and 1 month after treatment.
5. Attend all follow-up appointments and complete all required blood tests (liver function, lipid panel).
6. Avoid prolonged sun exposure during treatment.
7. Store at room temperature, away from moisture and sunlight. Keep out of reach of children.
FAQs
Do I need a prescription for Arynoin Isotretinoin 20mg?
Yes — isotretinoin is prescription-only and must be supervised by a qualified dermatologist. We will not dispense without a valid prescription.
Is isotretinoin safe during pregnancy?
NO — isotretinoin is absolutely contraindicated during pregnancy. It causes severe birth defects. Use two forms of contraception throughout treatment and for 1 month after stopping. Never take if pregnant or planning to become pregnant.
What monitoring is required during Arynoin treatment?
Regular blood tests (liver function, lipid panel) are required throughout treatment. Follow your dermatologist's monitoring schedule strictly. Do not skip any scheduled tests or appointments.
What are the contraindications for Arynoin?
Arynoin is contraindicated in pregnant or breastfeeding women, women of childbearing potential not using contraception, patients on tetracyclines, hepatic insufficiency, elevated blood lipids, hypervitaminosis A, and hypersensitivity to isotretinoin.
Can isotretinoin cause mood changes?
Rare reports of depression and mood changes have been associated with isotretinoin use. Report any mood changes, unusual feelings, or psychological symptoms to your dermatologist immediately.
How does Arynoin compare to other isotretinoin brands?
Arynoin contains Isotretinoin BP 20mg — the same active ingredient as other isotretinoin brands. Your dermatologist will prescribe the most appropriate brand for your treatment. Explore the full isotretinoin range and acne scar treatments at derma.pk.
Customer Reviews
Am using this from January. But thats my first purchase with Derma.pk
My purging phase just ended and am not getting any new acne. Some old acne still persist with dark spots but of course i need to complete my course of 11 months.
Don't take it without doctor advice. If you do, you must stock up Vaseline petroleum jelly and tons of moisturizer and drink plenty of water to avoid dryness.
Am pairing it with skinoren to treat dark spots
Excellent for skincare and personal needs.
Long-lasting expiry, very happy.
Excellent for sensitive skin needs.
Excellent customer support throughout.
