CLERET GEL (CLINDAMYCIN PHOSPHATE + TRETINOIN) 20gm FOR ACNE TREATMENT
CLERET GEL (CLINDAMYCIN PHOSPHATE + TRETINOIN) For the Treatment of Serve to Moderate Acne, For External Use
Cleret Gel is designed for the topical treatment of acne vulgaris in individuals aged 12 and above
It combines two active ingredients, Clindamycin Phosphate, and Tretinoin, to target acne from different angles
The gel minimizes percutaneous absorption of tretinoin, reducing the likelihood of systemic effects
Common adverse reactions include dry skin, nasal symptoms, and mild local skin responses
Users are advised to protect their skin from excessive sun exposure and exercise caution when using certain concomitant medications
Cleret Gel: Comprehensive Overview and Usage Guide
Description:
Cleret Gel is a unique blend of Clindamycin Phosphate, a water-soluble antibiotic, and Tretinoin, a retinoid. Clindamycin inhibits bacterial protein synthesis, while Tretinoin decreases microcomedo formation and promotes follicular cell turnover.
Composition:
Each gram contains:
- Clindamycin Phosphate 1.20% w/w
- Tretinoin 0.0259% w/w
Indications:
Primarily for topical treatment of acne vulgaris in patients aged 12 years and older.
Pharmacokinetics:
Cleret Gel shows minimal percutaneous absorption of Tretinoin. Plasma concentrations for Tretinoin generally range from 1.0 to 1.6 ng/mL, while Clindamycin concentrations usually stay below 3.5 ng/mL.
Dosage and Administration:
Apply a peasized amount at bedtime to the affected areas, gently spreading over the entire face. Avoid contact with eyes, mouth, nose angles, and mucous membranes.
Contraindications:
Avoid use in patients with regional enteritis, ulcerative colitis, or a history of antibiotic-associated colitis.
Warnings and Precautions:
Discontinue Cleret Gel if significant diarrhea occurs. Use sunscreen during treatment due to increased skin sensitivity to sunlight.
Adverse Reactions:
Common reactions include nasopharyngitis, dry skin, and local skin reactions like erythema, scaling, itching, burning, and stinging.
Drug Interactions:
Use medicated soaps or cosmetics with strong drying effects cautiously. Avoid concomitant use with erythromycin-containing products.
Use in Specific Populations:
Use during pregnancy only if the potential benefit justifies the risk. Limited data exists for pediatric and geriatric use.
Nonclinical Toxicology:
No observed teratogenicity in animal studies. Cleret Gel shows no carcinogenic effects, but Tretinoin may enhance photo cocarcinogenicity with UV radiation.
Presentation:
Supplied in 20-gram tubes, available by prescription only.
Instructions:
Store below 25 °C, protect from light and freezing, and keep away from children. For external use only.
Cleret Gel offers an effective topical solution for acne vulgaris. Adhering to administration guidelines and heeding warnings ensures safe and effective usage. Always consult healthcare professionals for personalized advice.
Cleret Gel is used primarily for the treatment of acne vulgaris. Its combination of Clindamycin Phosphate and Tretinoin works to reduce acne breakouts, control inflammation, and promote skin cell turnover. Regular use can lead to clearer, healthier skin and improved skin texture.Usage and Benefits of Cleret Gel
Usage:
Benefits:
Follow these steps to effectively use Cleret Gel for acne treatment:How to Use Cleret Gel for Acne Treatment
Cleret Gel is primarily used for the topical treatment of acne vulgaris. It combines Clindamycin Phosphate, an antibiotic, and Tretinoin, a retinoid, to effectively reduce acne breakouts, control inflammation, and promote healthy skin cell turnover. Cleret Gel works by inhibiting bacterial growth and reducing inflammation. The Clindamycin Phosphate targets acne-causing bacteria, while Tretinoin accelerates the turnover of skin cells, preventing the formation of acne lesions and improving overall skin texture. Cleret Gel is suitable for most skin types but should be used with caution if you have sensitive skin. It’s recommended to perform a patch test before applying it to the entire face to avoid irritation. Always consult a dermatologist for advice on use, especially if you have any pre-existing skin conditions. Apply a small, pea-sized amount of Cleret Gel to clean, dry skin at bedtime. Gently spread the gel over the affected areas of your face, avoiding contact with your eyes, mouth, and sensitive areas. For best results, use it consistently as prescribed by your doctor, and always follow up with sunscreen during the day to prevent increased sun sensitivity. Common side effects of Cleret Gel include skin dryness, irritation, redness, or a mild burning sensation. If any of these side effects persist or worsen, discontinue use and consult your healthcare provider. Serious reactions like significant diarrhea may also occur, in which case treatment should be discontinued.Frequently Asked Questions (FAQs)
What is Cleret Gel used for?
How does Cleret Gel work?
Is Cleret Gel suitable for all skin types?
How should I apply Cleret Gel for the best results?
Are there any side effects associated with Cleret Gel?