Depurch 25mg Tablet – Agomelatine for Depression, Sleep & Mood Regulation
- Depurch 25mg Tablets contain Agomelatine, a unique antidepressant that regulates mood and sleep.
- Acts on melatonin and serotonin receptors to restore circadian rhythm.
- Improves sleep quality and emotional stability in depression and anxiety.
- Prescription-required antidepressant available at Derma.pk across Pakistan.
- Ensured authenticity with supervision from licensed pharmacists and doctors.

Depurch 25mg Tablet – Agomelatine for Depression, Sleep Regulation, and Emotional Balance
Depurch 25mg Tablet contains Agomelatine, a novel antidepressant designed to treat major depressive disorder, anxiety, and sleep-related disturbances. Agomelatine works by acting as an agonist on melatonin receptors (MT1 and MT2) and an antagonist on serotonin receptors (5-HT2C). This dual mechanism helps restore the brain’s natural circadian rhythm, improve sleep quality, and regulate mood effectively.
Unlike traditional antidepressants, Agomelatine does not cause significant daytime drowsiness or sexual side effects. By balancing serotonin and melatonin activity, it improves both mental well-being and sleep-wake patterns, addressing two major components of depression — emotional imbalance and sleep disturbance.
Depurch 25mg is generally taken once daily at bedtime. It helps patients manage depressive symptoms such as sadness, fatigue, and anxiety while promoting natural relaxation and improved sleep continuity. Common side effects include mild headache, nausea, or dizziness, which usually subside with continued use. Regular liver function tests may be recommended during treatment to monitor safety.
How to Buy from Derma.pk
Visit Derma.pk to purchase Depurch 25mg Tablets. We provide delivery all over Pakistan. Since this is a prescription-only medicine, please email your prescription to sales@derma.pk or contact via WhatsApp at +92-320-5999650. Derma.pk is a licensed pharmacy ensuring genuine, safe, and high-quality medicines.
Usage & Benefits
- Effectively treats major depressive disorder and anxiety.
- Improves sleep quality by regulating melatonin activity.
- Helps restore normal circadian rhythm and emotional balance.
- Reduces symptoms of insomnia linked with depression.
- Promotes mental clarity, mood stability, and overall well-being.
How to Use Depurch 25mg Tablet
- Take one Depurch 25mg Tablet daily at bedtime, or as prescribed by your doctor.
- Swallow the tablet whole with a glass of water; do not chew or crush it.
- Take it at the same time each night to maintain stable melatonin activity.
- Do not stop taking Depurch suddenly without consulting your doctor.
- If you miss a dose, take it as soon as possible unless it’s near your next dose—then skip the missed one.
FAQs
- Q: What is Depurch 25mg used for?
A: Depurch 25mg Tablet is used to treat depression, anxiety, and sleep disorders. It helps restore normal sleep cycles and improves mood by acting on melatonin and serotonin receptors. - Q: How does Depurch 25mg work?
A: Depurch contains Agomelatine, which acts as a melatonin receptor agonist and serotonin receptor antagonist. This mechanism helps regulate mood and improve sleep quality. - Q: Can Depurch 25mg cause drowsiness?
A: Depurch 25mg helps normalize sleep patterns without causing daytime drowsiness. It is usually taken at bedtime for best results. - Q: Do I need a prescription to buy Depurch 25mg?
A: Yes, Depurch 25mg is a prescription medication. You must provide a valid prescription to purchase it from Derma.pk. - Q: Is Depurch 25mg safe for long-term use?
A: Depurch is safe under medical supervision. Regular monitoring of liver function is advised during long-term treatment to ensure safety.