Hyzonate 500 mg Injection (Hydrocortisone Sodium Succinate)
- Fast-acting hydrocortisone sodium succinate for injection.
- Used in emergency conditions like adrenal crisis, severe allergic reactions, asthma, and systemic inflammation.
- Administer via IV or IM after proper reconstitution.
- Prescription-only corticosteroid—use under medical supervision.
- Manufactured by Amson Pharma (Pvt.) Ltd, Pakistan.

Hyzonate 500 mg Injection – Potent Emergency Corticosteroid Therapy
Hyzonate 500 mg Injection contains hydrocortisone sodium succinate, a potent corticosteroid designed for rapid systemic action in critical care settings. It is essential when oral administration isn’t feasible and immediate anti-inflammatory or immunosuppressive effects are required.
This injectable steroid is vital in managing acute adrenal insufficiency (adrenal crisis), severe allergic reactions such as anaphylaxis, critical asthma exacerbations, severe inflammatory flares, systemic autoimmune conditions like systemic lupus erythematosus, and severe dermatological or gastrointestinal inflammations like Stevens-Johnson syndrome or ulcerative colitis.
Dosing depends on the clinical scenario: in severe cases, adults may receive 100-500 mg IV or IM every 2–6 hours, adjusted by response and medical supervision. Children require weight-based dosing and should be dosed with utmost caution.
While life-saving, improper or prolonged use carries risks including adrenal suppression, hyperglycemia, fluid retention, hypertension, immunosuppression, and impaired wound healing. It must be administered only under professional supervision with appropriate tapering.
How to Buy Hyzonate 500 mg Injection at Derma.pk
To purchase Hyzonate 500 mg Injection, visit Derma.pk, your reliable online pharmacy in Pakistan. After adding the product to your cart, proceed through the secure checkout for swift, nationwide delivery. A valid prescription is required for purchase. For assistance, reach out to us via sales@derma.pk or WhatsApp at +92-320-5999650. Get genuine, properly handled injectable medications delivered safely to your door.
Usage & Benefits
- Rapid Corticosteroid Effect: Provides immediate relief during critical inflammatory and allergic conditions.
- Emergency Steroid Replacement: Stabilizes adrenal function during adrenal crises and surgical stress.
- Flexible Administration: Can be given IV or IM, depending on urgency and setting.
- Hospital Essential: A mainstay in emergency medicine, critical care, and surgical wards.
- Life-Saving Therapy: Trusted for swift intervention in life-threatening scenarios.
How to Use Hyzonate 500 mg Injection
- Reconstitute the vial with sterile water as instructed—ensure complete dissolution.
- Administer via IV or IM depending on clinical judgment.
- Adults (acute situations): 100-500 mg every 2–6 hours based on condition and response.
- Pediatric dosing should be calculated by a licensed physician using weight-based protocols.
- Do not cease abruptly—gradual tapering is essential to prevent adrenal insufficiency.
Frequently Asked Questions
- Q: What conditions require Hyzonate 500 mg Injection?
It’s used for adrenal crisis, severe allergic reactions, critical asthma attacks, systemic inflammation, and steroid replacement when oral intake isn’t possible. - Q: Is a prescription needed?
Yes, this is a prescription-only injectable medication. - Q: Can children receive it?
Yes, but dosing is strictly weight-based and must be supervised by a healthcare professional. - Q: What are potential side effects?
They include immunosuppression, fluid balance issues, hypertension, blood sugar changes, adrenal suppression, and delayed wound healing. Use with careful monitoring.
