LOTDIS TABLETS 5mg PACK OF 10 TABLETS
LOTDIS TABLETS (Desloratadine USP )
A Lotdis contains Desloratadine, offering non-sedating relief from allergies
It’s indicated for allergic rhinitis and chronic idiopathic urticaria symptoms
For adults and those 12 and older, the recommended dose is one 5mg tablet daily
A Lotdis is generally well-tolerated, with mild side effects, including dry mouth and fatigue
Keep your A Lotdis tablets below 30 °C, away from heat, light, and moisture, and out of reach of children
A LOTDIS TABLETS (Desloratadine) Your Guide to This Allergy Relief Medicine
Description:
A LOTDIS TABLETS, also known as Desloratadine, is a chemical compound with the IUPAC name 2chloro6,11dihydro11(4piperidinylidene)5Hbenzo<5,6> cycloheptane<1,2b> pyridine It has a molecular formula of C19H19ClN and a molecular weight of 3108
Composition:
Each filmcoated tablet contains Desloratadine at a strength of 5mg
Indications:
A Lotdis tablets are primarily indicated for the symptomatic relief of:
Allergic rhinitis (both seasonal and perennial)
Chronic idiopathic urticaria
Dosage and Administration:
For adults and children aged 12 and above with normal hepatic and renal functions, the recommended dosage is one tablet (5mg) once daily For those with hepatic and renal dysfunction, the dosing frequency should be reduced to one 5mg tablet every two days
Children under 12 years of age should avoid using Lotdis tablets as their safety and efficacy have not been studied in this age group
Mode of Action:
Desloratadine, a long acting tricyclic histamine antagonist, works by selectively antagonizing H1receptor histamine activity It inhibits histamine release from human mast cells in vitro and does not easily cross the bloodborne barrier
Pharmacokinetics:
Absorption: Desloratadine's mean time to maximum plasma concentration is approximately 3 hours after a 5mg dose
Metabolism / Distribution: It is extensively metabolized to an active metabolite, 3hydroxydesloratadine, which is later glucuronidase
Elimination: The mean elimination half life of desloratadine is 27 hours, and approximately 87% is excreted in urine and feces
Pharmacokinetics in Special Population Groups:
Hepatically impaired patients: Patients with hepatic impairment experience approximately a 24fold increase in AUC compared to normal individuals
Renally impaired patients: Renal impairment leads to increases in C max and AUC values, with severe impairment causing greater increases
Patients over 65 tend to have slightly higher C max and AUC values than younger individuals.
Contraindications:
Individuals with a known hypersensitivity to desloratadine or any of its ingredients should not take Lotdis tablets.
Toxicity or Side Effects:
Lotdis tablets are a breeze to take, with side effects that are no worse than taking a sugar pill. In fact, most people who take Lotdis don't experience any side effects at all. And if you do, they're usually pretty mild, like a headache or upset stomach.
Dysmenorrhea
Pharyngitis
Dry mouth
Myalgia
Fatigue
Somnolence
Precautions:
- Do not give Lotdis tablets to children under 12 years of age.
- Geriatric patients: No need to adjust the dosage.
- Pregnant women should only use Lotdis tablets if absolutely necessary, as they are classified as a pregnancy category C medication.
Carcinogenicity, Mutagenicity & Fertility Impairment:
Desloratadine does not have carcinogenic or mutagenic properties, and it does not impact fertility
Over dosage:
While overdosing on desloratadine is uncommon, if it happens, take standard removal measures and provide symptomatic and supportive treatment.
Drug Interactions:
Erythromycin: Coad ministration of desloratadine with erythromycin can result in increased plasma concentrations of desloratadine and its metabolite
Storage:
Keep Lotdis tablets in a cool, dry place out of sunlight and reach of children.
Presentation:
Lotdis tablets are available in packs containing 10 tablets
Usage and Benefits of A LOTDIS Tablets
- Effective for Allergy Relief: Provides long-lasting relief from sneezing, itching, and runny nose caused by allergies.
- Helps Control Chronic Urticaria: Alleviates the discomfort of hives, reducing swelling and itching.
- Non-Sedating: Unlike some antihistamines, Desloratadine does not cause drowsiness, making it suitable for daily use.
- Convenient Dosage: Only one tablet per day for adults and children over 12 years of age.
How to Use A LOTDIS Tablets
To use A LOTDIS Tablets, take one tablet (5mg) once daily. It is recommended to take the tablet with or without food at the same time each day for best results. If you have liver or kidney problems, consult your healthcare provider to adjust the dosage.
- Dosage: 1 tablet daily for adults and children over 12 years old.
- For liver/kidney issues: One tablet every two days.
- Precautions: Do not use for children under 12 years of age.
- Storage: Keep in a cool, dry place, out of sunlight, and away from children.
1. What is A LOTDIS Tablets used for?
A LOTDIS Tablets (Desloratadine) are used for the symptomatic relief of allergic rhinitis (seasonal and perennial) and chronic idiopathic urticaria (hives). It helps alleviate symptoms like sneezing, runny nose, and itching caused by allergies.
2. How does A LOTDIS Tablets work?
Desloratadine, the active ingredient in A LOTDIS, works by blocking histamine activity, which helps reduce allergy symptoms like itching, swelling, and redness. It is a long-acting antihistamine that targets the H1 receptor and prevents histamine release from mast cells.
3. What is the recommended dosage of A LOTDIS Tablets?
The recommended dosage for adults and children 12 years and older is one 5mg tablet once daily. For those with liver or kidney impairment, the dosage may be adjusted to one tablet every two days. It is not recommended for children under 12 years.
4. Are there any side effects of A LOTDIS Tablets?
Most people do not experience side effects, but mild ones like headache, upset stomach, dry mouth, or fatigue can occur. If you experience more severe symptoms, contact a healthcare provider immediately.
5. Can A LOTDIS Tablets be taken during pregnancy?
A LOTDIS Tablets are classified as a pregnancy category C medication. They should only be used during pregnancy if absolutely necessary, and under the guidance of a healthcare provider.