Paromax CR 25mg Tablets (Paroxetine Controlled-Release)
Paromax CR 25mg contains Paroxetine Hydrochloride in a controlled-release SSRI formulation for once-daily dosing with reduced GI side effects. Prescribed for major depression, generalised anxiety disorder, OCD, panic disorder, and PTSD. Prescription-only medicine — submit valid prescription to Derma.pk for verified nationwide dispensing.
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Paromax Cr 25mg Tablets (paroxetine Controlled-release)
Description
Paromax CR 25mg Tablets — Paroxetine Controlled-Release
Paromax CR 25mg contains Paroxetine Hydrochloride in a controlled-release formulation — a Selective Serotonin Reuptake Inhibitor (SSRI) that maintains steady plasma levels throughout the day. The CR design reduces peak plasma fluctuations, minimising GI side effects compared to immediate-release paroxetine.
Prescribed for Major Depressive Disorder (MDD), Generalised Anxiety Disorder (GAD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Post-Traumatic Stress Disorder (PTSD), Social Anxiety Disorder, and PMDD. Once-daily dosing supports long-term adherence.
Key Clinical Points
- Strongest CYP2D6 inhibitor among SSRIs — review all co-medications before prescribing
- Never discontinue abruptly — taper gradually to avoid discontinuation syndrome (dizziness, brain zaps, irritability)
- Anticholinergic profile — monitor in elderly patients
- Full therapeutic effect typically observed after 2-4 weeks of consistent dosing
- Weight gain and sexual side effects may occur with long-term use — discuss with prescriber
Important Safety Information
This is a prescription-only medicine. Do not use without a valid prescription. Always consult your doctor or psychiatrist before starting, adjusting, or stopping Paromax CR. Submit your prescription to Derma.pk via email at sales@derma.pk or WhatsApp +92-320-5999650 for verified dispensing nationwide.
Browse our full range of antidepressants and psychiatric medications or all prescription medicines at Derma.pk.
Usage & Benefits
- Controlled-release paroxetine maintains steady plasma levels throughout the day for sustained antidepressant effect
- Effective across multiple indications: MDD, GAD, OCD, Panic Disorder, PTSD, Social Anxiety, PMDD
- Once-daily dosing improves medication adherence for long-term psychiatric management
- Lower GI side effect profile compared to immediate-release paroxetine formulations
- Improves mood stability, sleep quality, concentration, and reduces anxiety-driven physical symptoms
How To Use
Take one tablet of Paromax CR 25mg daily in the morning with a full glass of water. Swallow whole — do not crush, chew, or split the controlled-release tablet. Take at the same time each day for steady serotonin levels. Do not stop abruptly — always taper under medical supervision to avoid discontinuation syndrome. Continue treatment as prescribed even when symptoms improve. This is a prescription medicine — use only under the supervision of a qualified doctor or psychiatrist.
FAQs
What is Paromax CR 25mg used for?
It is prescribed for Major Depressive Disorder (MDD), Generalised Anxiety Disorder (GAD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, PTSD, Social Anxiety Disorder, and PMDD.
Why is the controlled-release formulation preferred?
The CR formulation provides steady plasma concentrations throughout the day, reducing peak-related side effects such as nausea and sedation, and supports once-daily dosing convenience.
Can I stop Paromax CR 25mg suddenly?
No. Paroxetine has one of the highest risks of discontinuation syndrome among SSRIs. Symptoms include dizziness, electric shock sensations (brain zaps), irritability, and flu-like feelings. Always taper slowly under medical supervision.
What drug interactions should I be aware of?
Paroxetine is a potent CYP2D6 inhibitor — it can significantly raise blood levels of drugs metabolised by this enzyme (e.g., certain antipsychotics, antiarrhythmics, TCAs). Always inform your prescriber of all medications before starting.



