Silo M 50/1000mg Tablet – Sitagliptin + Metformin for Type 2 Diabetes
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Description
Silo M 50/1000mg Tablet – Sitagliptin + Metformin Combination for Type 2 Diabetes
Silo M 50/1000mg Tablets are a fixed-dose combination containing Sitagliptin 50mg and Metformin 1000mg, manufactured by Macter International. This higher-strength combination is prescribed for type 2 diabetic patients who require more aggressive blood sugar control or who have progressed beyond the starter 500mg Metformin dose. The two active ingredients work through complementary mechanisms: Sitagliptin inhibits DPP-4 to preserve incretin hormones and stimulate insulin release, while Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity.
By combining both drugs in a single tablet, Silo M 50/1000mg simplifies the treatment regimen, improves patient compliance, and delivers comprehensive glycaemic control across both fasting and post-meal glucose levels. This fixed-dose combination also ensures consistent co-dosing — a critical advantage in multi-drug diabetes management.
Patients initiating combination therapy may start with Silo M 50/500mg and step up to the 1000mg variant as clinically indicated. For patients who only need Sitagliptin monotherapy, Silo 50mg is available separately. All Silo variants are stocked at Derma.pk with authentic supply and delivery nationwide including Lahore, Karachi, and Islamabad.
How to Order Silo M 50/1000mg Tablet at Derma.pk
Order from derma.pk. Contact sales@derma.pk or WhatsApp +92-320-5999650. A valid prescription is required for purchase.
Usage & Benefits
- Dual Mechanism: Two complementary drugs in one tablet for comprehensive blood sugar control.
- Improved Compliance: Single combination tablet replaces two separate medications.
- Fasting & Post-Meal Control: Targets both baseline and peak glucose levels throughout the day.
- Metformin Benefit: May support modest weight reduction and improve insulin sensitivity.
- Established Safety: Both active ingredients have well-documented safety and efficacy profiles.
How To Use
1. Take as prescribed — typically twice daily with meals to reduce stomach upset.
2. Swallow the tablet whole with a glass of water. Do not crush or chew.
3. Maintain a consistent schedule for best blood sugar management.
4. Follow a healthy diet and regular physical activity as part of your treatment plan.
5. Do not stop without consulting your doctor, even if blood sugar levels appear normal.
FAQs
What is the difference between Silo M 50/1000mg and 50/500mg?
The 1000mg variant contains twice the Metformin dose. It is prescribed when patients need stronger glucose lowering, particularly if 500mg is no longer sufficient.
Why take it with food?
Metformin can cause nausea or stomach upset if taken on an empty stomach. Taking with food minimises this side effect.
Can Silo M cause low blood sugar?
The combination alone rarely causes hypoglycaemia. Risk increases with insulin or sulfonylurea co-administration.
Is kidney function relevant?
Yes. Metformin is contraindicated in severe renal impairment. Your doctor will check kidney function before prescribing.
Is a prescription required?
Yes. This is a prescription-only diabetes medicine.
