TERBISAN CREAM 10g
TERBISAN CREAM (Terbinafine HCI Cream JP 1% w/w, Broad Spectrum Anti-Fungal)
Terbisan Cream, with Terbinafine HCI, offers a powerful and broad-spectrum solution against fungal infections of the skin
Available in both tablet and cream forms, Terbisan provides flexibility in treating various fungal infections, offering oral and topical options for patients
The cream’s fungicidal action, inhibiting the formation of squalene epoxidase, makes Terbisan stand out in effectively treating dermatophytes and other fungal pathogens
With less than 5% absorption after topical application, Terbisan Cream ensures targeted action on the skin, minimizing systemic exposure and potential side effects
From tinea infections to onychomycosis, Terbisan addresses a range of fungal conditions, making it a versatile and comprehensive antifungal solution
Terbisan Cream: A Comprehensive Overview
Composition:
TERBISAN CREAM (1% w/w):
Terbinafine HCI USP in a Cream base
Physiochemical Properties:
Terbinafine
Hydrochloride: Broad spectrum antifungal, fungicidal at low concentrations,
soluble in organic solvents, slightly soluble in water
Mechanism of Action:
Terbinafine inhibits
squalene epoxidase, disrupting ergosterol synthesis, leading to damaged fungal
cell membranes Fungicidal action sets it apart from fungistatic alternatives
Pharmacokinetics:
Cream: Minimal
absorption (less than 5%) after topical application
Indications:
Cream: For fungal
infections of the skin caused by various pathogens, including candida albican
and pityriasis versicolor
Dosage & Administration:
Cream: Applied twice
daily, duration varies for different infections
Contraindications:
Hypersensitivity to cream ingredient
Precautions:
Special caution for
tablets in patients with chronic liver dysfunction or impaired renal failure
Cream for external
use only; avoid contact with eyes
Pregnancy and Lactation:
Limited data in
pregnant women; tablets not recommended during pregnancy Excreted in breast
milk; not recommended in nursing mothers
Side Effects:
- Cream: Occasional
redness, itching, and stinging at the application site
Over dosage:
cream: Symptoms
include nausea, vomiting, abdominal pain, dizziness, rash, frequent urination,
and headache Treatment involves eliminating the drug and symptomatic support
Presentation:
Cream: Terbisan 1%,
10gm collapsible aluminum tube
Storage:
Cream: Store below
30 °C, for external use only
To be sold on prescription of a registered medical
practitioner only For oral use (tablets) and external use (cream) only