TERBISAN TABLETS 125mg | 10 TABLETS
TERBISAN TABLETS (Terbinafine tablet USP)
Terbisan Tablets contain Terbinafine HCI USP, known for its broad-spectrum antifungal properties against skin, hair, and nail infections caused by dermatophytes
With its fungicidal action, Terbinafine sets itself apart by disrupting ergosterol synthesis, a crucial step in fungal cell membrane formation, leading to their destruction
These tablets show rapid absorption, peak concentration in 2 hours, and widespread distribution in dermis, sebum, and nails, ensuring effective treatment
Terbisan Tablets effectively combat a range of fungal infections, from onychomycosis to tinea pedis and corporis, offering versatile solutions
Caution is advised in specific conditions like chronic liver dysfunction or renal failure, and it’s contraindicated in cases of hypersensitivity to its ingredients
Terbisan Tablets: A Comprehensive Overview
Composition Terbisan Tablets:
Terbisan Tablets(125mg/250mg): Terbinafine HCI USP
Physiochemical Properties:
Terbinafine Hydrochloride: Broad spectrum antifungal, fungicidal at low concentrations, soluble in organic solvents, slightly soluble in water
Mechanism of Action:
Terbinafine inhibits squalene epoxidase, disrupting ergosterol synthesis, leading to damaged fungal cell membranes Fungicidal action sets it apart from fungistatic alternatives
Pharmacokinetics:
Tablets: Rapid absorption, peak concentration in 2 hours, binds to plasma proteins (99%), distributed in dermis, sebum, and nails
Indications:
Tablets: Fungal infections of skin, hair, and nails caused by dermatophytes Also for onychomycosis, tinea pedis, corporis, cruris, capitis, and cutaneous candidiasis
Dosage & Administration:
Tablets: Varied duration depending on infection and severity Children and adults with different doses Hair and scalp infections treated for 4 weeks
Contraindications Terbisan :
Hypersensitivity to any tablet or cream ingredient
Precautions Terbisan Tablets:
Special caution for tablets in patients with chronic liver dysfunction or impaired renal failure
Pregnancy and Lactation:
Limited data in pregnant women; tablets not recommended during pregnancy Excreted in breast milk; not recommended in nursing mothers
Side Effects:
Tablets: Mild to moderate and transient side effects Common ones include gastrointestinal events, liver enzyme abnormalities, skin rashes, visual and taste disturbances
Over dosage:
Tablets: Symptoms include nausea, vomiting, abdominal pain, dizziness, rash, frequent urination, and headache Treatment involves eliminating the drug and symptomatic support
Presentation Terbisan Tablets:
(125 mg/250 mg), blister strip of 10 Tablets
Conclusion: