TERBISAN TABLETS 125mg | 10 TABLETS
TERBISAN TABLETS (Terbinafine tablet USP)
Terbisan Tablets contain Terbinafine HCI USP, known for its broad-spectrum antifungal properties against skin, hair, and nail infections caused by dermatophytes
With its fungicidal action, Terbinafine sets itself apart by disrupting ergosterol synthesis, a crucial step in fungal cell membrane formation, leading to their destruction
These tablets show rapid absorption, peak concentration in 2 hours, and widespread distribution in dermis, sebum, and nails, ensuring effective treatment
Terbisan Tablets effectively combat a range of fungal infections, from onychomycosis to tinea pedis and corporis, offering versatile solutions
Caution is advised in specific conditions like chronic liver dysfunction or renal failure, and it’s contraindicated in cases of hypersensitivity to its ingredients
Terbisan Tablets: A Comprehensive Overview
Composition Terbisan Tablets:
Terbisan Tablets(125mg/250mg): Terbinafine HCI USP
Physiochemical Properties:
Terbinafine Hydrochloride: Broad spectrum antifungal, fungicidal at low concentrations, soluble in organic solvents, slightly soluble in water
Mechanism of Action:
Terbinafine inhibits squalene epoxidase, disrupting ergosterol synthesis, leading to damaged fungal cell membranes Fungicidal action sets it apart from fungistatic alternatives
Pharmacokinetics:
Tablets: Rapid absorption, peak concentration in 2 hours, binds to plasma proteins (99%), distributed in dermis, sebum, and nails
Indications:
Tablets: Fungal infections of skin, hair, and nails caused by dermatophytes Also for onychomycosis, tinea pedis, corporis, cruris, capitis, and cutaneous candidiasis
Dosage & Administration:
Tablets: Varied duration depending on infection and severity Children and adults with different doses Hair and scalp infections treated for 4 weeks
Contraindications Terbisan :
Hypersensitivity to any tablet or cream ingredient
Precautions Terbisan Tablets:
Special caution for tablets in patients with chronic liver dysfunction or impaired renal failure
Pregnancy and Lactation:
Limited data in pregnant women; tablets not recommended during pregnancy Excreted in breast milk; not recommended in nursing mothers
Side Effects:
Tablets: Mild to moderate and transient side effects Common ones include gastrointestinal events, liver enzyme abnormalities, skin rashes, visual and taste disturbances
Over dosage:
Tablets: Symptoms include nausea, vomiting, abdominal pain, dizziness, rash, frequent urination, and headache Treatment involves eliminating the drug and symptomatic support
Presentation Terbisan Tablets:
(125 mg/250 mg), blister strip of 10 Tablets
Conclusion:
Usage and Benefits of Terbisan Tablets
- Effective for Skin and Nail Infections: Terbisan is highly effective in treating dermatophyte infections like athlete's foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris), as well as fungal nail infections (onychomycosis).
- Fungicidal Action: Unlike fungistatic treatments, Terbisan kills the fungus, providing more reliable results in treating persistent fungal infections.
- Convenient Dosage: Terbisan offers a once-daily dosage, simplifying the treatment regimen for better patient compliance.
- Broad-Spectrum Activity: It works against a wide range of fungal pathogens, including dermatophytes, molds, and dimorphic fungi, making it a versatile antifungal treatment.
- Well-Tolerated: Terbisan is generally well-tolerated with minimal side effects, especially when used as directed.
How to Use Terbisan Tablets
Follow these guidelines for the correct usage of Terbisan Tablets:
- Take Terbisan Tablets orally with or without food, as directed by your healthcare provider.
- The usual dosage is 250mg once daily. For nail infections, the treatment period can extend to several weeks (usually 6-12 weeks for onychomycosis).
- For scalp and skin infections, the typical duration is 4 weeks. Do not exceed the recommended dosage, and always complete the prescribed course of treatment, even if symptoms improve before the course is finished.
- If you miss a dose, take it as soon as you remember, but do not double the dose to make up for a missed one.
Ensure to monitor for side effects and consult your healthcare provider if any occur during treatment.
1. What is Terbisan used for?
Terbisan Tablets (Terbinafine HCl) are used to treat fungal infections of the skin, hair, and nails caused by dermatophytes. It is effective in treating conditions like onychomycosis (fungal nail infections), tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm), and cutaneous candidiasis.
2. How does Terbisan work?
Terbisan works by inhibiting the enzyme squalene epoxidase in the fungal cell membrane. This prevents the synthesis of ergosterol, a vital component of the fungal cell membrane, ultimately leading to fungal cell death. Terbisan has fungicidal activity, meaning it kills the fungus rather than just stopping its growth.
3. What is the recommended dosage for Terbisan Tablets?
The dosage of Terbisan Tablets depends on the infection being treated. For skin and nail infections, the typical dose is 250mg once daily. Treatment durations vary: for hair and scalp infections, it is typically 4 weeks. Always follow your healthcare provider's instructions for the correct dosage and duration.
4. Are there any side effects of Terbisan Tablets?
Common side effects of Terbisan include gastrointestinal issues (nausea, abdominal pain), liver enzyme abnormalities, skin rashes, and disturbances in taste or vision. Most side effects are mild and transient, but severe reactions can occur. If you experience unusual symptoms, consult your healthcare provider immediately.
5. Can Terbisan be used during pregnancy or breastfeeding?
Terbisan Tablets are not recommended during pregnancy due to limited safety data. They are also excreted in breast milk, so it is advised not to use them while breastfeeding. Always consult your healthcare provider before taking any medication during pregnancy or while nursing.